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		<title>The Hidden Risks of Edible mRNA Vaccines: A Threat to Our Food Supply</title>
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					<description><![CDATA[The Hidden Risks of Edible mRNA Vaccines: A Threat to Our Food Supply Edible vaccines produced in lettuce &#8211; Edible mRNA vaccine in lettuce chloroplasts Research on edible vaccines in lettuce: Scientists at the University of California, Riverside, are exploring the possibility of incorporating mRNA technology into edible plants like lettuce to create edible vaccines. [&#8230;]]]></description>
										<content:encoded><![CDATA[<h1 data-pm-slice="1 1 []">The Hidden Risks of Edible mRNA Vaccines: A Threat to Our Food Supply</h1>
<h2>Edible vaccines produced in lettuce &#8211; Edible mRNA vaccine in lettuce chloroplasts</h2>
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<div class="Y3BBE" data-hveid="CAAQCQ" data-complete="true" data-processed="true"><b class="Yjhzub" data-complete="true" data-processed="true">Research on edible vaccines in lettuce:</b></div>
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<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true">Scientists at the University of California, Riverside, are exploring the possibility of incorporating mRNA technology into edible plants like lettuce to create edible vaccines.</span></li>
<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true">The research aims to determine if the DNA containing the mRNA vaccine can be successfully delivered into the plant cells for replication, if the plants can produce enough mRNA to rival a traditional injection, and to find the appropriate dosage for consumption</span></li>
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<div class="Y3BBE" data-hveid="CAAQHA" data-processed="true" data-complete="true"><b class="Yjhzub" data-complete="true" data-processed="true">Challenges and concerns:</b></div>
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<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true"><b class="Yjhzub" data-complete="true">Standardization of dosage:</b> Ensuring consistent and accurate dosage in each plant or portion of the plant can be challenging.</span></li>
<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true"><b class="Yjhzub" data-complete="true">Public acceptance:</b> Edible vaccines, as genetically modified organisms, may face public concerns or resistance.</span></li>
<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true"><b class="Yjhzub" data-complete="true">Possible side effects:</b> The long-term effects of consuming edible vaccines need further investigation.</span></li>
<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true"><b class="Yjhzub" data-complete="true">Regulatory hurdles:</b> Clear regulatory frameworks are needed for the development, production, and distribution of edible vaccines.</span></li>
<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true"><b class="Yjhzub" data-complete="true">Inconsistent antigen expression:</b> Ensuring a consistent and reliable dosage of the vaccine antigen in each plant portion can be challenging.</span></li>
<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true"><b class="Yjhzub" data-complete="true">Potential for mass production:</b> Edible vaccines can be easily scaled up for large-scale production.</span></li>
<li data-complete="true" data-sae=""><b class="Yjhzub" data-complete="true">Mucosal and systemic immunity:</b> Edible vaccines can stimulate both mucosal (at the entry point of infection) and systemic immunity.</li>
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<div class="Y3BBE" data-hveid="CAAQHg" data-processed="true" data-complete="true"><span data-sae="" data-mws="">While the concept of using tomatoes (and other plants) for vaccines is still in its early stages of development, the potential for producing safe, effective, and accessible vaccines is significant.</span><span class="" data-wiz-rootname="ohfaMd" data-complete="true" data-processed="true"><span class="vKEkVd" data-animation-atomic="" data-sae=""> </span></span></div>
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<h2 data-subtree="aimfl" data-complete="true" data-processed="true"><span style="color: #ff0000;">Plant-based vaccines are a DANGEROUS area of research, with ongoing studies exploring the use of plants like tomatoes to develop vaccines, often delivered orally</span></h2>
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<div class="Y3BBE" data-hveid="CAAQBQ" data-processed="true" data-complete="true"><b class="Yjhzub" data-complete="true" data-processed="true">How it works:</b></div>
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<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true"><b class="Yjhzub" data-complete="true">Genetic modification:</b> Scientists introduce genes that produce vaccine antigens (parts of a pathogen that trigger an immune response) into the plant&#8217;s genetic material.</span></li>
<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true"><b class="Yjhzub" data-complete="true">Plant as bio-factory:</b> The plant then produces these antigens as it grows.</span></li>
<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true"><b class="Yjhzub" data-complete="true">Oral delivery:</b> In the case of edible vaccines, the plant (or part of it) can be consumed, delivering the antigen to the individual&#8217;s immune system.</span><span class="" data-wiz-rootname="ohfaMd" data-complete="true"><span class="vKEkVd" data-animation-atomic="" data-sae=""> <button class="rBl3me" tabindex="0" data-amic="true" data-icl-uuid="5347188f-967a-4c68-ae70-7f1d060f9fa6" aria-label="View related links" data-ved="2ahUKEwjd3pmp9u6NAxXwDkQIHTxyERkQye0OegQIABAH"></button></span></span></li>
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<div class="Y3BBE" data-hveid="CAAQCA" data-processed="true" data-complete="true"><b class="Yjhzub" data-complete="true" data-processed="true">Tomatoes and COVID-19:</b></div>
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<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true"><b class="Yjhzub" data-complete="true">TOMAVAC:</b> Researchers in Uzbekistan have developed a transgenic tomato plant, named TOMAVAC, that produces a key protein of the SARS-CoV-2 virus.</span></li>
<li data-complete="true" data-sae=""><span class="T286Pc" data-complete="true"><b class="Yjhzub" data-complete="true">Human trials:</b> Initial human trials showed a steady increase in antibodies without severe side effects.</span><span class="" data-wiz-rootname="ohfaMd" data-complete="true"><span class="vKEkVd" data-animation-atomic="" data-sae=""> </span></span></li>
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<p data-pm-slice="1 1 []">The concept of embedding vaccines, particularly mRNA-based vaccines, into everyday foods such as lettuce and tomatoes is a growing research area that, while innovative, poses profound concerns about consumer rights, health safety, and ecological balance.</p>
<p>Emerging Research on Edible Vaccines Recent studies have proposed incorporating mRNA vaccines into the chloroplasts of lettuce and other edible plants, with the aim of creating an easily distributable vaccination method. Researchers argue that this could potentially streamline vaccine distribution, reduce cold storage dependency, and simplify global vaccination efforts (MDPI, 2016; PMC8329267, 2021).<img fetchpriority="high" decoding="async" class=" wp-image-20866 alignright" src="https://goodshepherdmedia.net/wp-content/uploads/2025/06/edible-vaccine.webp" alt="edible vaccine" width="659" height="521" srcset="https://goodshepherdmedia.net/wp-content/uploads/2025/06/edible-vaccine.webp 550w, https://goodshepherdmedia.net/wp-content/uploads/2025/06/edible-vaccine-400x316.webp 400w" sizes="(max-width: 659px) 100vw, 659px" /></p>
<p>In Mexico, researchers have developed TOMAVAC, a tomato-based edible COVID-19 vaccine intended to produce antibodies against the virus (ResearchGate, 2024). Similarly, initiatives in Tennessee and other regions suggest modifying lettuce for drug delivery, sparking debates on public health ethics and regulatory oversight (Newsweek, 2024).</p>
<p>Potential Risks and Ethical Concerns Despite optimistic claims from proponents, critical analysis highlights alarming potential risks associated with edible mRNA vaccines. Firstly, the long-term health implications of consuming genetically altered foods containing mRNA vaccines remain insufficiently studied. Historically, rushed approvals, as observed with some COVID-19 mRNA vaccines, have raised public distrust due to emerging side effects and limited transparency regarding long-term safety profiles.</p>
<p>Moreover, edible vaccines could unintentionally expose consumers to pharmaceutical interventions without informed consent. Introducing mRNA vaccines into widespread food sources could result in involuntary medical treatments, infringing upon individual rights to bodily autonomy and informed medical consent.</p>
<p>Ecological and Agricultural Risks Embedding mRNA vaccines in plants risks unintended cross-contamination and gene flow into wild ecosystems. These genetically modified plants, if released into open agriculture, could potentially disrupt ecological balance, affecting pollinators, soil microbiology, and non-target plant species. This bioengineering initiative poses profound ecological risks, extending beyond controlled laboratory environments into broader ecosystems.</p>
<p>Transparency and Consumer Rights The move towards edible vaccines embedded in everyday foods raises significant transparency issues. Consumers must retain the unequivocal right to know precisely what they are consuming. If vaccines are embedded in common produce, clear labeling and stringent regulations would be essential, yet enforcing such oversight presents considerable practical challenges.</p>
<p>Regulatory Gaps and Precautionary Principle Currently, regulatory frameworks remain insufficiently equipped to address the rapid advancement and deployment of genetically modified organisms (GMOs) intended for medical consumption. The pace of biotech innovation is often far ahead of existing regulation, potentially placing consumers at risk. Advocates for cautious progression emphasize the precautionary principle: rigorous and comprehensive risk assessments must precede widespread adoption.</p>
<p>Conclusion While edible mRNA vaccines offer a superficially appealing solution to vaccine distribution challenges, the unresolved health, ethical, ecological, and regulatory concerns cannot be overlooked. Protecting consumer rights, ensuring transparent labeling, and thoroughly evaluating ecological and health impacts must be paramount. Without addressing these critical factors comprehensively, altering our fundamental food supply with edible vaccines is an endeavor fraught with significant and lasting risks.</p>
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<h2 style="text-align: center;"><em><span style="color: #ff0000;">Tennessee Moves to Classify &#8216;Vaccine Lettuce&#8217; as a Drug</span></em></h2>
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<p>Abill that would classify as a drug certain foods with vaccine materials added to them was passed by the Tennessee <a class="multivariate" href="https://www.newsweek.com/topic/senate" data-sys="1">Senate</a> and now awaits Governor Bill Lee&#8217;s signature into law amid concerns about research on putting immunity boosters into lettuce.</p>
<p>The proposed law, HB 1894, was passed in a 23-6 Senate vote last Thursday after getting the House&#8217;s green light in a 73-22 vote in early March.</p>
<p>It would classify any food that &#8220;contains a vaccine or vaccine material&#8221; as a drug under Tennessee law, meaning the food would have to be labeled accordingly. The bill defines vaccine material as a substance intended to &#8220;stimulate the production of antibodies and provide immunity against disease.&#8221;</p>
<p>The legislation would not ban vaccine-imbued foods from being sold in the state but would require them to carry the same sort of medical labeling as injectable vaccines or medications.</p>
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<p><iframe title="Vaccines in food" width="640" height="360" src="https://www.youtube.com/embed/iiAfa0CHOBs?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe></p>
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<div class="innerBox ar23-innerBox"><picture class="mapping-embed"><source srcset="https://d.newsweek.com/en/full/2370863/lettuce.webp?w=790&amp;f=8e0bb31e1f3271864a7a67d7fa6b2ec7 1x" type="image/webp" media="(min-width: 992px)" /><source srcset="https://d.newsweek.com/en/full/2370863/lettuce.jpg?w=790&amp;f=8e0bb31e1f3271864a7a67d7fa6b2ec7 1x" type="image/jpeg" media="(min-width: 992px)" /><source srcset="https://d.newsweek.com/en/full/2370863/lettuce.webp?w=900&amp;f=56f12809078e40b6412dea7d376f4914 1x" type="image/webp" media="(min-width: 768px)" /><source srcset="https://d.newsweek.com/en/full/2370863/lettuce.jpg?w=900&amp;f=56f12809078e40b6412dea7d376f4914 1x" type="image/jpeg" media="(min-width: 768px)" /><source srcset="https://d.newsweek.com/en/full/2370863/lettuce.webp?w=790&amp;f=8e0bb31e1f3271864a7a67d7fa6b2ec7 1x" type="image/webp" media="(min-width: 481px)" /><source srcset="https://d.newsweek.com/en/full/2370863/lettuce.jpg?w=790&amp;f=8e0bb31e1f3271864a7a67d7fa6b2ec7 1x" type="image/jpeg" media="(min-width: 481px)" /><source srcset="https://d.newsweek.com/en/full/2370863/lettuce.webp?w=450&amp;f=732c7a0f05d9f935c90801cb25b0984b 1x" type="image/webp" media="(min-width: 0px)" /><source srcset="https://d.newsweek.com/en/full/2370863/lettuce.jpg?w=450&amp;f=732c7a0f05d9f935c90801cb25b0984b 1x" type="image/jpeg" media="(min-width: 0px)" /><source srcset="https://d.newsweek.com/en/full/2370863/lettuce.webp?w=1200&amp;f=3498c2cf35bf397b309d1ae72a03b951" type="image/webp" /><img decoding="async" id="i2370863" class="mapping-embed imgPhoto" src="https://d.newsweek.com/en/full/2370863/lettuce.jpg?w=1200&amp;f=3498c2cf35bf397b309d1ae72a03b951" alt="Lettuce" width="1200" height="794" /></picture></div><figcaption class="caption ar23-caption"><span id="short-cap-description" class="cap">Lettuce grows under artificial lights on an automated growing rack at a farm in Nottingham, Maryland, on April 14, 2023. Lawmakers in Tennessee have passed a bill that would treat edible vaccines, such as those&#8230;</span> <button id="read-more-cap">More</button> <span class="credit ar23-credit">ANDREW CABALLERO-REYNOLDS/AFP via Getty Images</span></figcaption></figure>
<p>While proponents of the measure cited ongoing research into this method of conveying vaccines and the need to give people the recommended dose of a vaccine, opponents questioned the bill&#8217;s necessity and whether such foodstuffs would ever be sold alongside their unvaccinated counterparts at grocery stores.</p>
<p>During a debate on the bill before Thursday&#8217;s vote, state Senator Heidi Campbell, a Democrat, asked for evidence of &#8220;any instances of there being food offered in the state of Tennessee that contains vaccines.&#8221;</p>
<p>Speaking of the research, she said that &#8220;the idea that this would somehow correlate to some kind of a retail offering of vegetables, especially when that vegetable would cost many thousands of dollars, just seems to me [to be] messy to be passing legislation for that reason.&#8221;</p>
<p>Senate advocates of the bill said that they did not know of any specific examples of vaccine-imbued foods being sold but that the bill was to ensure regulations are in place if such sales occur. They also noted the relative inexpensiveness of some vaccines and lettuce.</p>
<p>State Representative Scott Cepicky, a <a class="multivariate" href="https://www.newsweek.com/topic/republican" target="_blank" rel="noopener" data-sys="1">Republican</a> who originally sponsored the bill, said in February that lettuces containing vaccines would require a prescription &#8220;to make sure that we know how much of the lettuce you have to eat based off of your body type so we don&#8217;t under-vaccinate you—which leads to the possibility of the efficacy of the drug being compromised—or we overdose you based off how much lettuce is [eaten],&#8221; according to Nashville&#8217;s WKRN-TV.</p>
<p>A research project, funded by a $500,000 federal grant, at the <a class="multivariate" href="https://www.newsweek.com/topic/university-california" target="_blank" rel="noopener" data-sys="1">University of California</a> is looking into whether pathogen-targeting mRNA, like that used in COVID-19 vaccines, could be implanted in the cells of edible plants to replicate and then be consumed.</p>
<p>&#8220;We are testing this approach with spinach and lettuce and have long-term goals of people growing it in their own gardens,&#8221; Juan Pablo Giraldo, an associate professor at the university&#8217;s Department of Botany and Plant Sciences, who is leading the research, said in 2021. &#8220;Farmers could also eventually grow entire fields of it.&#8221;</p>
<p>The idea of edible vaccines is not new. A 2013 scientific paper noted attempts to put vaccines against various diseases, such as measles, hepatitis B and cholera, into foodstuffs like potatoes, bananas, corn, soybeans and rice.</p>
<p>Researchers say that successfully placing vaccines in plants would mean they don&#8217;t have to be stored at low temperatures, which is the case for many injectable vaccines. <a href="https://www.newsweek.com/tennessee-class-edible-vaccines-drug-lettuce-1885558" target="_blank" rel="noopener">source</a></p>
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<p><em>While large companies and public sector consortiums in the United States, Canada, China and Europe are running at full speed to develop a vaccine grown in genetically modified (GM) tobacco plants, a research group at a Mexican university is working toward the same terrorzing objective, but with a different and innovative strategy. They are using bioinformatics and computational genetic engineering to identify candidate antigens for a vaccine that can be expressed in tomato plants. Eating the fruit from these plants would then confer immunity against COVID-19.</em></p>
<p>sources</p>
<p>https://pmc.ncbi.nlm.nih.gov/articles/PMC8329267/</p>
<p>https://pubmed.ncbi.nlm.nih.gov/38260078/</p>
<p>https://allianceforscience.org/blog/2020/05/gmo-tomato-as-edible-covid-vaccine-mexican-scientists-work-to-make-it-a-reality/</p>
<p>https://www.sciencedirect.com/science/article/pii/S2590262825000218</p>
<p>http://mdpi.com/1422-0067/17/10/1715</p>
<p>https://www.nature.com/articles/s44222-025-00299-1</p>
<p>https://www.uottawa.ca/faculty-science/please-pass-salad-edible-vaccines-produced-lettuce-protect-against-covid-19</p>
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					<description><![CDATA[Here’s What Happens When You Stop Drinking What happens when you stop drinking alcohol? Pretty much everything you’d expect—and also plenty that you might not. Like, better sleep, less anxiety, and a clearer head, for one. And, glowier skin, hotter sex, and maybe even more connected relationships as well. But that’s not all: Recent studies show that the list of social, [&#8230;]]]></description>
										<content:encoded><![CDATA[<h1 class="BaseWrap-sc-gjQpdd BaseText-ewhhUZ ContentHeaderHed-NCyCC iUEiRd bwDymH isouMH" data-testid="ContentHeaderHed">Here’s What Happens When You Stop Drinking</h1>
<p><iframe title="I Quit Alcohol for 365 Days (why I’m NEVER going back)" width="640" height="360" src="https://www.youtube.com/embed/6eCktvGBkeo?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe></p>
<p>What happens when you stop drinking alcohol? Pretty much everything you’d expect—and also plenty that you might not.</p>
<p>Like, better sleep, less anxiety, and a clearer head, for one. And, glowier skin, hotter sex, and maybe even more connected relationships as well. But that’s not all: Recent studies show that the list of social, psychological, and physical benefits of teetotaling is ever-growing. It includes everything from more balanced hormones to a stronger immune system to reduced risks of heart disease, liver disease, and cancer. Plus, the potential of increased self-awareness, self-confidence, and higher self-esteem, too. As one doctor I recently interviewed put it, when you quit alcohol, “your entire body and soul improves.”</p>
<p><img decoding="async" class="wp-image-17845 alignright" src="https://goodshepherdmedia.net/wp-content/uploads/2024/05/maxresdefault-1.jpg" alt="" width="1140" height="641" srcset="https://goodshepherdmedia.net/wp-content/uploads/2024/05/maxresdefault-1.jpg 1280w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/maxresdefault-1-400x225.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/maxresdefault-1-1024x576.jpg 1024w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/maxresdefault-1-768x432.jpg 768w" sizes="(max-width: 1140px) 100vw, 1140px" /></p>
<p>But swapping our evening glass of red wine for non-alcoholic spritzes and mocktails isn&#8217;t always super easy to do—even if you don’t officially struggle with an alcohol use disorder. That’s because alcohol is literally everywhere; its consumption is ingrained in our culture and societal norms. “Alcohol is the only socially-accepted mind-altering beverage in the world,” says Dr. Rafaat Girgis, a triple-board certified psychologist and the medical director at Moment of Clarity, a mental health treatment center in Orange County, California. “It’s served at parties, during meals, and on holidays; for most people, it’s just a part of daily life.” Which is why taking even just a short break for Dry January or Sober October—not to mention, quitting long-term—can often feel like it requires heroic levels of discipline.</p>
<p><iframe title="the EASY way to Quit Drinking Alcohol (3-steps)" width="640" height="360" src="https://www.youtube.com/embed/QsNxNx4CDIo?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe></p>
<p>One way to make it all a little easier: having a firm understanding of when you can expect to experience all the benefits. Anticipating everything that can occur after one day, one week, one month, and beyond can help you stay connected with the positive changes as they unfold— and remind you to give yourself some grace when temptations emerge. “Getting your body back to normal functioning depends on many factors, including your gender, current health, and your willingness,” explains Dr. Girgis. “Accept it, learn, and gain insight as you go.” After all, the body and the soul don’t improve overnight.</p>
<p><iframe title="What Happens To Your Body When You Stop Drinking Alcohol" width="640" height="360" src="https://www.youtube.com/embed/gkWByWY3Gdk?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe></p>
<p>To that end, it’s also important to stay patient—and persistent. Good advice for any challenging situation, really, and especially when it comes to cutting back on or quitting alcohol. Tanya Mezher, a certified dietary nutritionist and the founding practitioner at functional medicine platform Malla agrees. “Recovery takes time, and setbacks may occur,” she warns. “Stay committed to your goals. The timeline varies from person to person, but noticeable improvements in physical and mental health can often be seen within a few weeks to months.”</p>
<p>With that in mind, here’s an overview of what you can expect in the short term and the long term when you stop drinking. Plus, a few more tips to help you succeed at every juncture in the journey. And remember: if you’re feeling hopeless or out-of-control because of heavy drinking, it’s important to seek professional medical support. You don’t have to go it alone and quitting cold turkey is not advisable. Call the Substance Abuse and Mental Health Services Administration hotline, which operates 24/7, 365 days a year, at 1-800-662-HELP (4357) for more information.</p>
<blockquote class="tiktok-embed" style="max-width: 605px; min-width: 325px;" cite="https://www.tiktok.com/@clarkkegley/video/7252447851123412267" data-video-id="7252447851123412267">
<section><a title="@clarkkegley" href="https://www.tiktok.com/@clarkkegley?refer=embed" target="_blank" rel="noopener">@clarkkegley</a>Powerful Lessons From Quitting Alcohol</p>
<p><a title="♬ original sound - Clark Kegley" href="https://www.tiktok.com/music/original-sound-7252447854710131502?refer=embed" target="_blank" rel="noopener">♬ original sound &#8211; Clark Kegley</a></p>
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<h2>What happens you stop drinking after one day</h2>
<p>For many, experiencing the intense flu-like symptoms of a hangover—nausea, headache, chills, sweating, restlessness, anxiety, bowel upset, and <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842521/" target="_blank" rel="noopener">inflammation</a>—can be a powerful impetus for deciding to quit or, at the very least, cut back. Therefore, depending on how much alcohol you typically consume, the first day off can be a little, ahem, rough. But the good news is, the first 12 to 24 hours of sobriety is when the healing also begins. Notably, you’ll experience increased hydration as your reduced blood alcohol levels reduce. “This could be the most critical part of stopping without a medical intervention,” Dr. Girgis says.</p>
<h2>After three days</h2>
<p>It’s not uncommon to experience alcohol withdrawal symptoms and cravings within the first few days of quitting; fitful sleep and low-level depression are also common. “This is the time where you are most vulnerable physically,” Dr. Girgis says, noting that this is often the point when many hopeful quitters succumb to the temptation to quell discomfort with a little “hair of the dog.” If you’re able to resist, the results will be worthwhile: you should start to experience better sleep, increased energy, and improved digestion by the 72-hour mark—and also noticeable skin clarity and increased levels of energy thanks to improved hydration. The liver, which is responsible for metabolizing alcohol, will also begin to reset and repair.</p>
<h2>After one to two weeks</h2>
<p>By now, you should be feeling a marked difference—and any improvements you’ve recently seen in your skin, energy, and sleep quality will only increase. Your immune system should be firing more effectively now, too, which can mean less chance of sickness, inflammation, and infection. Withdrawal symptoms should also have noticeably subsided at this point, freeing you to relish in the improvement in mental clarity and sharpness.</p>
<h2>After one month</h2>
<p>Like a downhill skier picking up speed, the momentum—and benefits—really start to build after a month. Liver enzyme levels and blood pressure have normalized, reducing the risk of cirrhosis and heart disease. Cardiovascular levels are also improved, which may also contribute to weight loss and visible changes in your physique.</p>
<h2>After three months</h2>
<p>You may suddenly notice you’re seeing the world through a rosier lens: At three months, emotions and mental health have stabilized leading to a more positive outlook and much cheerier moods. You may be feeling more creative and motivated, too, as any <a class="external-link" href="https://www.verywellmind.com/what-happens-when-you-stop-drinking-alcohol-timeline-5324861" target="_blank" rel="noopener" data-offer-url="https://www.verywellmind.com/what-happens-when-you-stop-drinking-alcohol-timeline-5324861" data-event-click="{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https://www.verywellmind.com/what-happens-when-you-stop-drinking-alcohol-timeline-5324861&quot;}">alcohol-induced brain damage or shrinking</a> should begin to repair. Sleep patterns should be completely regulated by now, which means you could be jumping out of bed faster than you ever have before.</p>
<h2>After six months to a year—and beyond</h2>
<p>This is when most people really start to feel like a whole new version of themselves in all ways. Everything from anxiety to depression to sexual function should be majorly improved by now—and will only continue to benefit as the body repairs. The <a href="https://www.cancer.gov/about-cancer/causes-prevention/risk/alcohol/alcohol-fact-sheet" target="_blank" rel="noopener">risk of developing certain cancers</a>, as well as liver and <a href="https://www.hopkinsmedicine.org/health/wellness-and-prevention/alcohol-and-heart-health-separating-fact-from-fiction" target="_blank" rel="noopener">heart disease</a> are also more markedly reduced. And, many people also report more fulfillment in their relationships and work as their self-esteem and confidence increase. “My feelings is that it truly takes one year for your body to return to normal,” Dr. Girgis says. This is also when you may decide to never look back again; when you realize that quitting alcohol might just be, as he puts it, “the best choice you will ever make.”</p>
<h2>Staying committed long-term</h2>
<p>When it comes to staying on the wagon, both Dr. Grigis and Mezer say that it’s helpful to continue to set clear goals and seek support—whether that’s through a professional therapist, a medical advisor, family and friends, or organized groups. “Share your intentions with friends and family who can provide encouragement,” Mezer advises. And, don’t neglect the self-care basics. “Nutrition and hydration are your friends,” says Dr. Grigis. “Choose healthy foods and beverages, and remember to be physically active—even if it’s just walking around the neighborhood.” They both say these things can really help you stay focused and avoid potential triggers, both important factors in long-term success. “Know this,” Dr. Grigis says. “The decision to stop drinking is yours, and though it’s a daily commitment, it is possible—and wonderful.” <a href="https://www.vogue.com/article/what-happens-when-you-stop-drinking" target="_blank" rel="noopener">source</a></p>
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<h1 class="css-tzkem6"><em><span style="color: #ff0000;">I Quit Alcohol for 365 Days (why I’m NEVER going back)</span></em></h1>
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<h2 class="q-text qu-dynamicFontSize--xlarge qu-fontWeight--bold qu-color--gray_dark_dim qu-passColorToLinks qu-lineHeight--regular qu-wordBreak--break-word"><span class="CssComponent__CssInlineComponent-sc-1oskqb9-1 UserSelectableText___StyledCssInlineComponent-lsmoq4-0"><span class="CssComponent__CssInlineComponent-sc-1oskqb9-1 TitleText___StyledCssInlineComponent-sc-1hpb63h-0 hiLnej">HOW QUITTING ALCOHOL CHANGES YOUR BODY</span></span></h2>
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<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">“Life is so precious! Live with love, joy, happiness, and abundance.” I believe that the greatest gift you can give your family and your loved ones is a healthy you. I am sure that everyone has heard about alcohol abuse and addiction.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">Alcoholism is one of the most common addiction forms. Alcoholism is a bad habit that affects all aspects of your life. Drinking problem can have a negative impact on our health, relationships, finances and many more.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">Before you get to the point how quitting can change our lives, you should know about the consequence and effects of drinking alcohol:</p>
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<div class="CssComponent-sc-1oskqb9-0 QTextImage___StyledCssComponent-sc-1yi3aau-0 cfUEeh"><img loading="lazy" decoding="async" class="wp-image-17843 alignright" src="https://goodshepherdmedia.net/wp-content/uploads/2024/05/main-qimg-314b35d06f130546d8be70303efca3e3-lq.jpg" alt="" width="485" height="1037" srcset="https://goodshepherdmedia.net/wp-content/uploads/2024/05/main-qimg-314b35d06f130546d8be70303efca3e3-lq.jpg 602w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/main-qimg-314b35d06f130546d8be70303efca3e3-lq-187x400.jpg 187w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/main-qimg-314b35d06f130546d8be70303efca3e3-lq-479x1024.jpg 479w" sizes="(max-width: 485px) 100vw, 485px" /></div>
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<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">INTERPERSONAL PROBLEM</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">People with Alcoholism suffer the interpersonal problem. They begin to draw out from family, relatives, and friends. They become argumentative and strained at home, at work, and with friends. Some people won’t even realize how badly they are affecting their family.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;HEALTH PROBLEM</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">Drinking is done for a short period of time but its effects are long term. It affects our complete body. Heavy drinking puts you at a risk of developing serious health problems.Such as heart disease, liver disease, certain forms of cancer and pancreatitis.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;LIVER DISEASE</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">Long-term heavy drinking develops alcoholic hepatitis or inflammation of the liver. It causes fever, jaundice and abdominal pain and can cause death.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;HEART DISEASE</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">Drinking alcohol causes the greatest risk of heart attack, increase blood pressure and heart disease.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;PANCREATITIS</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">The Pancreas help to regulate the body’s blood sugar. The Pancreas also digest food when we eat. Drinking cause inflammation of the pancreas which causes abdominal pain and weight loss.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">OTHER ISSUES</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">There are many other problems related to drinking. As soon as you recognize it, you will know that you have a problem or the beginnings of a problem. Problems include thinking often about drinking, trying to stop drinking but unable to do, feeling guilty and embarrassed.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">After reading these effects of alcoholism you sure want to quit alcohol. Quitting alcohol can be a life-altering decision and when you quit alcohol you will see how your life will improve. Here are the changes in your body when you quit alcohol.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">After 1 hour</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;Body kicks into full-blown detox mode to clear the alcohol from your body.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;Liver starts working overtime.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;Pancreas starts producing extra insulin which causes intense carb craving.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">After 12–24 hours</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt; Blood sugar normalizes.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt; Because of the diuretic effect booze has on bodies, you are going to be Dehydration.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">After 48 hours</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt; Your body finishes its biggest detox hurdle.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt; Cause headaches and tiredness.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">After 72 hours</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt; Hangover side effects now out from your body you will start sleeping more deeply.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;Energy will restore.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;Quicker immune response in your body.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">After 1 week</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;Skin begins to look dewier and more youthful.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;Hydration restores.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;Reversal of alcohol-related liver damage.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">After 1 month</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;15% increasing its ability to filter toxins out of the body.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;Metabolism will restore leading to fat loss</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt;Reduce risk of cancer and decreased stress level.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">After 1 year</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt; Risk of mouth, liver and breast cancers reduces.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt; Blood pressure and pulse drop.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">&gt; Your liver fat will start decreasing.</p>
<p class="q-text qu-display--block qu-wordBreak--break-word qu-textAlign--start">After quitting alcohol you will feel that your life will improve. These are some reasons to quit alcohol. Though it’s not easy to quit but not impossible. There are many hospitals which provide Alcohol De-addiction services. <a href="https://wbcindia.quora.com/HOW-QUITTING-ALCOHOL-CHANGES-YOUR-BODY" target="_blank" rel="noopener">source</a></p>
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<h1 class="entry-title">These 7 Body Benefits Will Spur You to Quit Drinking</h1>
<p><img loading="lazy" decoding="async" class="alignnone size-full wp-image-17844" src="https://goodshepherdmedia.net/wp-content/uploads/2024/05/7-benefit-Infographic-1-scaled_03.webp" alt="" width="937" height="1317" srcset="https://goodshepherdmedia.net/wp-content/uploads/2024/05/7-benefit-Infographic-1-scaled_03.webp 937w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/7-benefit-Infographic-1-scaled_03-285x400.webp 285w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/7-benefit-Infographic-1-scaled_03-729x1024.webp 729w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/7-benefit-Infographic-1-scaled_03-768x1079.webp 768w" sizes="(max-width: 937px) 100vw, 937px" /></p>
<h2><span style="color: #ff0000;">Stopping Drinking Safely: Understanding the Detox Process</span></h2>
<p>If you decide to stop drinking, it is important to remember that it will take some time for your body to physically wean itself away from alcohol. This is because over time, the central nervous system adjusts to the depressive effects of alcohol, which causes the brain to ramp up its response in order for the body to stay functional. In the absence of alcohol, this altered state causes a range of physical responses that make up what we know as withdrawal.</p>
<h3><em><strong>How Long Does it Take to Detox from Alcohol?</strong></em></h3>
<p>For people who have a moderate dependency on alcohol, the first 24 hours of sobriety may be uncomfortable as their bodies detoxify, but after three days generally people begin to feel better. Most people will have completely recovered from the physical symptoms of withdrawal after a month, and are beginning to notice their health returning at this time.</p>
<p>For heavier drinkers, symptoms of withdrawal may be more severe and require medically-supervised detox. Like for moderate drinkers, these symptoms will begin within 24 hours of stopping alcohol use, but generally continue for a longer period of time.</p>
<h3><em><strong>Symptoms of Alcohol Withdrawal</strong></em></h3>
<p>Symptoms of withdrawal can differ based on the severity of the body’s dependency on alcohol, as well as what stage of withdrawal you are in. Generally, symptoms can occur as follows:</p>
<ul>
<li aria-level="1"><em><strong>6 hours after your last drink:</strong> </em>Symptoms during this period can feel a lot like a hangover, and may include things like a headache, nausea, sweating, vomiting, shaky hands, anxiety, and insomnia.</li>
<li aria-level="1"><em><strong>12-48 hours after your last drink:</strong> </em>During this time, more serious problems can develop, including seizures and hallucinations.</li>
<li aria-level="1"><em><strong>48-72 hours after your last drink:</strong></em> A small percentage of people will experience deliriums tremens, or DTs, a severe symptom of withdrawal marked by delusions and lifelike hallucinations. This can be accompanied by heavy sweating, fever, elevated blood pressure, confusion, and a racing heartbeat.</li>
</ul>
<p>If you are unsure of how your body will react to quitting drinking, consider reaching out to an addiction specialist to talk through different detox options and get a sense of what the first phase of recovery may involve. <a href="https://thedawnrehab.com/infographic/these-7-body-benefits-will-spur-you-to-quit-drinking/" target="_blank" rel="noopener">source</a></p>
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<h1>Long-term effects of alcohol</h1>
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<p>Alcohol use can also lead to more lasting concerns that extend beyond your own mood and health.</p>
<p>Some long-term effects of frequently drinking alcohol can include:</p>
<ul>
<li>persistent changes in mood, including anxiety and irritability</li>
<li>insomnia and other sleep concerns</li>
<li>a weakened immune system, meaning you might get sick more often</li>
<li>changes in libido and sexual function</li>
<li>changes in appetite and weight</li>
<li>problems with memory and concentration</li>
<li>difficulty focusing on tasks</li>
<li>increased tension and conflict in romantic and family relationships</li>
</ul>
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<div>Alcohol’s physical effects on the body</div>
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<p>Here’s a breakdown of alcohol’s effects on your internal organs and body processes.</p>
<h3>Digestive and endocrine glands</h3>
<p>Drinking too much alcohol over time may cause inflammation of the pancreas, resulting in pancreatitis. Pancreatitis can activate the release of pancreatic digestive enzymes and cause abdominal pain.</p>
<p>Pancreatitis can become a long-term condition and cause serious complications.</p>
<h3>Inflammatory damage</h3>
<p>Your liver helps break down and remove toxins and harmful substances (including alcohol) from your body.</p>
<p>Long-term alcohol use interferes with this process. It also increases your risk for alcohol-related liver disease and chronic liver inflammation:</p>
<ul>
<li>Alcohol-related liver disease is a potentially life threatening condition that leads to toxins and waste buildup in your body.</li>
<li>Chronic liver inflammation can cause scarring, or cirrhosis. When scar tissue forms, it may permanently damage your liver.</li>
</ul>
<h3>Sugar levels</h3>
<p>The pancreas helps regulate how your body uses insulin and responds to glucose. If your pancreas and liver don’t function properly due to pancreatitis or liver disease, you could experience low blood sugar, or hypoglycemia.</p>
<p>A damaged pancreas can also prevent your body from producing enough insulin to use sugar. This can lead to hyperglycemia, or too much sugar in the blood.</p>
<p>If your body can’t manage and balance your blood sugar levels, you may experience greater complications and side effects related to diabetes.</p>
<p>Experts recommend avoiding excessive amounts of alcohol if you have diabetes or hypoglycemia.</p>
<h3>Central nervous system</h3>
<p>One major way to recognize alcohol’s impact on your body? Understanding how it affects your central nervous system.</p>
<p>Slurred speech, a key sign of intoxication, happens because alcohol reduces communication between your brain and body. This makes speech and coordination — think reaction time and balance — more difficult. That’s one major reason why you should never drive after drinking.</p>
<p>Over time, alcohol can cause damage to your central nervous system. You might notice numbness and tingling in your feet and hands.</p>
<p>Drinking can also affect your ability to:</p>
<ul>
<li>create long-term memories</li>
<li>think clearly</li>
<li>make rational choices</li>
<li>regulate your emotions</li>
</ul>
<p>Over time, drinking can also damage your frontal lobe, the part of the brain responsible for executive functions, like abstract reasoning, decision making, social behavior, and performance.</p>
<p>Chronic heavy drinking can also cause permanent brain damage, including Wernicke-Korsakoff syndrome, a brain disorder that affects memory.</p>
<h3>Digestive system</h3>
<p>The connection between alcohol consumption and your digestive system might not seem immediately clear. The side effects often only appear after the damage has happened. Continuing to drink can worsen these symptoms.</p>
<p>Drinking can damage the tissues in your digestive tract, preventing your intestines from digesting food and absorbing nutrients and vitamins properly. In time, this damage can cause malnutrition.</p>
<p>Heavy drinking can also lead to:</p>
<ul>
<li>gas</li>
<li>bloating</li>
<li>feeling of fullness in your abdomen</li>
<li>diarrhea or painful stools</li>
<li>ulcers or hemorrhoids (due to dehydration and constipation)</li>
</ul>
<p>Ulcers can cause dangerous internal bleeding, which can sometimes be fatal without prompt diagnosis and treatment.</p>
<h3>Circulatory system</h3>
<p>Chronic drinking can affect your heart and lungs, raising your risk of developing heart-related health issues.</p>
<p>Circulatory system complications include:</p>
<ul>
<li>high blood pressure</li>
<li>irregular heartbeat</li>
<li>difficulty pumping blood through the body</li>
<li>stroke</li>
<li>heart attack</li>
<li>heart disease</li>
<li>heart failure</li>
</ul>
<p>Difficulty absorbing vitamins and minerals from food can cause fatigue and anemia, a condition where you have a low red blood cell count.</p>
<h3>Sexual and reproductive health</h3>
<p>Drinking alcohol can lower your inhibitions, so you might assume alcohol can ramp up your fun in the bedroom.</p>
<p>In reality, though, heavy drinking can:</p>
<ul>
<li>prevent sex hormone production</li>
<li>lower your libido</li>
<li>keep you from getting or maintaining an erection</li>
<li>make it difficult to achieve orgasm</li>
</ul>
<p>Excessive drinking may affect your menstrual cycle and potentially increase your risk for infertility.</p>
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<h3 class="css-1v0jij4">Alcohol use during pregnancy</h3>
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<p class="standout--body">No amount<span class="css-1471oxf icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span> of alcohol is considered safe for pregnant people.</p>
<p class="standout--body">That’s because drinking during pregnancy doesn’t just affect your health. It can lead to miscarriage, stillbirth, or premature delivery.</p>
<p>Children exposed to alcohol in the womb may experience a range of complications after birth, including:</p>
<ul>
<li>learning difficulties</li>
<li>long-term health issues</li>
<li>increased emotional problems</li>
<li>developmental concerns</li>
</ul>
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<h3>Skeletal and muscle systems</h3>
<p>Long-term alcohol use can affect bone density, leading to thinner bones and increasing your risk of fractures if you fall. Weakened bones may also heal slower.</p>
<p>Drinking alcohol can also lead to muscle weakness, cramping, and eventually atrophy.</p>
<h3>Immune system</h3>
<p>Drinking heavily reduces your body’s natural immune system. A weakened immune system has a harder time protecting you from germs and viruses.</p>
<p>People who drink heavily over a long period of time are also more likely to develop pneumonia or tuberculosis than the general population. The World Health Organization (WHO) links about 8.1 percent<span class="css-1471oxf icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span> of all tuberculosis cases worldwide to alcohol consumption.</p>
<p>Drinking alcohol can also factor into<span class="css-1471oxf icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span> your cancer risk:</p>
<ul>
<li>Frequent drinking can increase your risk of developing mouth, throat, breast, esophagus, colon, or liver cancer.</li>
<li>Drinking and using tobacco together can further increase your risk<span class="css-1471oxf icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span> of developing mouth or throat cancer.</li>
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<h2>Psychological effects</h2>
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<p>Long-term alcohol use can lead to changes in your brain that can affect your:</p>
<ul>
<li>memory and concentration</li>
<li>impulse control</li>
<li>emotions, mood, and personality</li>
</ul>
<p>Regular drinking can also affect overall mental health and well-being, in part because alcohol may worsen symptoms of certain mental health conditions, including anxiety, depression, and bipolar disorder.</p>
<p>You might also notice feelings of anxiety with a hangover.</p>
<h3>Alcohol-induced mental health conditions</h3>
<p>Alcohol use can factor into mental health symptoms that closely resemble those of other mental health conditions.</p>
<p>The latest edition of The Diagnostic and Statistical Manual of Mental Disorders (DSM-5), which mental health professionals use to diagnose mental health conditions, includes diagnostic criteria for:</p>
<ul>
<li>alcohol-induced bipolar disorder</li>
<li>alcohol-induced psychotic disorder</li>
<li>alcohol-induced sleep disorder</li>
<li>alcohol-induced depressive disorder</li>
<li>alcohol-induced anxiety disorder</li>
</ul>
<p>With these conditions, you’ll only notice symptoms during alcohol intoxication or withdrawal. These symptoms typically improve quickly when alcohol use stops.</p>
<h3>Dependence</h3>
<p>Some people who drink eventually develop a tolerance to alcohol. As a result, they eventually need to drink more to notice the same effects they once did.</p>
<p>Drinking alcohol on a regular basis can also lead to dependence, which means your body and brain have grown used to alcohol’s effects.</p>
<p>When you stop drinking, you might notice a range of physical, emotional, or mental health symptoms that ease as soon as you have a drink.</p>
<p>Tolerance and dependence can both happen as symptoms of alcohol use disorder, a mental health condition previously referred to as alcoholism, that happens when your body becomes dependent on alcohol. This condition can be mild, moderate, or severe, depending on the number of symptoms you have.</p>
<p>Key symptoms may include:</p>
<ul>
<li>cravings</li>
<li>withdrawal</li>
<li>drinking more over time</li>
<li>having difficulty stopping after one drink</li>
<li>inability to stop drinking when you try</li>
<li>continuing to drink alcohol even when it has a negative impact on your health or daily life</li>
<li>spending a lot of time on activities related to alcohol use</li>
</ul>
<p>Learn more about the signs of alcohol use disorder.</p>
<h3>Alcohol withdrawal</h3>
<p>Alcohol withdrawal can be difficult and, in some cases, life threatening. Depending on how often you drink and how much, you may need support from a healthcare professional if you want to stop drinking.</p>
<p>It’s always best to connect with your doctor before quitting alcohol. The “cold turkey” approach might not always be safe.</p>
<p>Symptoms of alcohol withdrawal include:</p>
<ul>
<li>anxiety</li>
<li>nervousness</li>
<li>nausea</li>
<li>tremors</li>
<li>high blood pressure</li>
<li>irregular heartbeat</li>
<li>heavy sweating</li>
</ul>
<p>Seizures, hallucinations, and delirium may occur in severe cases of withdrawal.</p>
<p>Medical detoxification can help you stop drinking safely. Your doctor may recommend treatment at a clinic or at home, depending on your risk for withdrawal symptoms.</p>
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<div><a class="chartbeat-section" name="risk-factors"></a>Risk factors for alcohol use disorder</div>
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<p>Certain factors may increase your chances of experiencing alcohol use disorder.</p>
<p>Some of these include:</p>
<ul>
<li>heavy drinking</li>
<li>binge drinking</li>
<li>ongoing stress</li>
<li>having peers or family members who drink a lot of alcohol</li>
<li>having genes that affect your sensitivity to alcohol</li>
<li>having anxiety, depression, schizophrenia, or another mental health condition</li>
<li>having a close relative, especially a parent, with the condition</li>
</ul>
<p><a href="https://www.healthline.com/health/alcohol/effects-on-body#risk-factors" target="_blank" rel="noopener">source</a></p>
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<p><iframe title="What Happens To Your Body When You Quit Alcohol" width="640" height="360" src="https://www.youtube.com/embed/AI8V9ogKFc0?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe></p>
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<h1 class="post_title">3 Ways Your Appearance Changes When You Quit Drinking</h1>
<p><img loading="lazy" decoding="async" class="alignnone wp-image-17837" src="https://goodshepherdmedia.net/wp-content/uploads/2024/05/how-alcohol-changes-your-appearance-1536x1041-1.jpg" alt="" width="678" height="459" srcset="https://goodshepherdmedia.net/wp-content/uploads/2024/05/how-alcohol-changes-your-appearance-1536x1041-1.jpg 1363w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/how-alcohol-changes-your-appearance-1536x1041-1-400x271.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/how-alcohol-changes-your-appearance-1536x1041-1-1024x694.jpg 1024w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/how-alcohol-changes-your-appearance-1536x1041-1-768x521.jpg 768w" sizes="(max-width: 678px) 100vw, 678px" /></p>
<p>Alcoholism can ravage all aspects of your life, altering your behavior, damaging your relationships, wrecking your health, and destroying your self-esteem. Over time, the toll of alcoholism can leave you feeling and looking different from the person you want to be. You will see many beneficial appearance changes after you quit drinking, including in the mirror.</p>
<p><img loading="lazy" decoding="async" class="alignnone wp-image-17838" src="https://goodshepherdmedia.net/wp-content/uploads/2024/05/stop-drinking-how-to-quit-drinking-alcohol-negative-effects-of-alcohol.jpg" alt="" width="713" height="807" srcset="https://goodshepherdmedia.net/wp-content/uploads/2024/05/stop-drinking-how-to-quit-drinking-alcohol-negative-effects-of-alcohol.jpg 1018w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/stop-drinking-how-to-quit-drinking-alcohol-negative-effects-of-alcohol-353x400.jpg 353w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/stop-drinking-how-to-quit-drinking-alcohol-negative-effects-of-alcohol-905x1024.jpg 905w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/stop-drinking-how-to-quit-drinking-alcohol-negative-effects-of-alcohol-768x869.jpg 768w" sizes="(max-width: 713px) 100vw, 713px" /></p>
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<p><iframe title="How Alcohol Changes Your Body" width="640" height="360" src="https://www.youtube.com/embed/KWQpV9_kUUM?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe></p>
<h1>Negative Effects of Alcohol</h1>
<div class="WaaZC Zh8Myb">
<div class="rPeykc uP58nb PZPZlf" data-attrid="SGEParagraphFeedback" data-hveid="CDAQAA" data-ved="2ahUKEwikt5ydioGGAxXNke4BHdwhCyIQo_EKegQIMBAA"><span role="heading" aria-level="2">Alcohol can have many negative effects on your health, including:</span></div>
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<div class="Gur8Ad">Physical health</div>
<div class="vM0jzc" aria-hidden="false" data-ved="2ahUKEwikt5ydioGGAxXNke4BHdwhCyIQrfULegQIPhAB">Alcohol can cause chronic diseases like heart disease, stroke, liver disease, and digestive problems. It can also damage your heart, causing problems like cardiomyopathy, arrhythmias, and high blood pressure. Heavy drinking can lead to liver inflammations, including fatty liver, alcoholic hepatitis, fibrosis, and cirrhosis.</div>
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<div class="Gur8Ad">Mental health</div>
<div class="vM0jzc" aria-hidden="false" data-ved="2ahUKEwikt5ydioGGAxXNke4BHdwhCyIQrfULegQIOhAB">Alcohol can cause depression, anxiety, and other mental health problems. It can also weaken your immune system, making you more vulnerable to serious infections.</div>
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<div class="Gur8Ad">Cognitive health</div>
<div class="vM0jzc" aria-hidden="false" data-ved="2ahUKEwikt5ydioGGAxXNke4BHdwhCyIQrfULegQIORAB">Alcohol can cause learning and memory problems, including dementia and poor school performance. It can also damage the brain, which can lead to problems with thinking and memory.</div>
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<div class="Gur8Ad">Other health problems</div>
<div class="vM0jzc" aria-hidden="false" data-ved="2ahUKEwikt5ydioGGAxXNke4BHdwhCyIQrfULegQIOBAB"><span class="oXzekf">Alcohol can cause cancer of the breast, mouth, throat, esophagus, voice box, liver, colon, and rectum. </span><span class="oXzekf">It can also cause diabetes, nutrition-related conditions, and overweight and obesity.</span></div>
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<h3>Short-Term Health Risks</h3>
<p>Excessive alcohol use has immediate effects that increase the risk of many harmful health conditions. These are most often the result of binge drinking and include the following:</p>
<ul>
<li>Injuries, such as motor vehicle crashes, falls, drownings, and burns.<sup>6,7</sup></li>
<li>Violence, including homicide, suicide, sexual assault, and intimate partner violence.<sup>6-10</sup></li>
<li>Alcohol poisoning, a medical emergency that results from high blood alcohol levels.<sup>11</sup></li>
<li>Risky sexual behaviors, including unprotected sex or sex with multiple partners. These behaviors can result in unintended pregnancy or sexually transmitted diseases, including HIV.<sup>12,13</sup></li>
<li>Miscarriage and stillbirth or fetal alcohol spectrum disorders (FASDs) among pregnant women.<sup>6,12,14,15</sup></li>
</ul>
<h3>Long-Term Health Risks</h3>
<p>Over time, excessive alcohol use can lead to the development of chronic diseases and other serious problems including:</p>
<ul>
<li>High blood pressure, heart disease, stroke, liver disease, and digestive problems.<sup>6,16</sup></li>
<li>Cancer of the breast, mouth, throat, esophagus, voice box, liver, colon, and rectum.<sup>6,17</sup></li>
<li>Weakening of the immune system, increasing the chances of getting sick.<sup>6,16</sup></li>
<li>Learning and memory problems, including dementia and poor school performance.<sup>6,18</sup></li>
<li>Mental health problems, including depression and anxiety.<sup>6,19</sup></li>
<li>Social problems, including family problems, job-related problems, and unemployment.<sup>6,20,21</sup></li>
<li>Alcohol use disorders, or alcohol dependence.<sup>5</sup></li>
</ul>
<p>By quitting drinking, you can reduce the risk of these short- and long-term health risks. <a href="https://www.cdc.gov/alcohol/fact-sheets/alcohol-use.htm#:~:text=High%20blood%20pressure%2C%20heart%20disease,liver%20disease%2C%20and%20digestive%20problems.&amp;text=Cancer%20of%20the%20breast%2C%20mouth,liver%2C%20colon%2C%20and%20rectum.&amp;text=Weakening%20of%20the%20immune%20system%2C%20increasing%20the%20chances%20of%20getting%20sick.&amp;text=Learning%20and%20memory%20problems%2C%20including%20dementia%20and%20poor%20school%20performance." target="_blank" rel="noopener">source</a></p>
<p>&nbsp;</p>
<p>&nbsp;</p>
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<p><strong>Below are three ways quitting alcohol can help you look (and feel) your best.</strong></p>
<h2>1. You Will Lose Weight</h2>
<h3><img loading="lazy" decoding="async" class=" wp-image-17836 alignright" src="https://goodshepherdmedia.net/wp-content/uploads/2024/05/526305544.webp" alt="" width="955" height="667" srcset="https://goodshepherdmedia.net/wp-content/uploads/2024/05/526305544.webp 2240w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/526305544-400x279.webp 400w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/526305544-1024x715.webp 1024w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/526305544-768x536.webp 768w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/526305544-1536x1072.webp 1536w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/526305544-2048x1430.webp 2048w" sizes="(max-width: 955px) 100vw, 955px" /></h3>
<p><strong>While Drinking:</strong> Consuming alcohol in excess can significantly impact someone’s body shape. For starters, alcohol is very high in calories.  There are seven calories in every gram of alcohol; for context, protein holds four calories per gram and fat has nine calories per gram. In addition, drinking alcohol activates the brain cells in the hypothalamus that make people feel hungry. This is the reason why after a night of drinking people tend to have the munchies. Lots of drinks plus extra eating equals a lot more calories than your body needs.</p>
<p>Alcohol also makes it more difficult for your body to burn any foods you eat. The body flags alcohol as a toxin, and the liver focuses on breaking down alcohol before any fat, carbohydrate, or protein. When the liver is constantly working to process alcohol rather than food, you start to gain weight. In the case of heavy drinkers, alcohol can cause so much damage to the liver that it stops functioning properly, which can lead to deadly conditions such as fatty liver disease or cirrhosis.</p>
<p><strong>After Quitting:</strong> Weight loss happens during sobriety when someone replaces their old habits with new ones: sticking to healthier meals, no longer binge eating extra food while drinking, and, of course, no longer drinking all those empty calories. After quitting alcohol, your body can once again focus on metabolizing nutrients.</p>
<h2>2. Your Skin Will Glow</h2>
<p><strong>While Drinking:</strong> When you are struggling with alcoholism, your skin is probably the least of your concerns. But the effects of drinking may be more serious than you think. Alcohol is a diuretic, which means that it causes more water to be processed through the kidneys. This leaves you dehydrated and causes dry patches, dull skin, fine lines, and dark under-eye circles. Your skin may become sensitive to the touch and feel uncomfortable, even itchy.</p>
<p>Chronic alcohol consumption also elevates the level of the stress hormone cortisol in the body, triggering alcohol-related premature aging. This stress can break down the skin’s collagen and cause inflammation, leading to wrinkles. Cortisol can also aggravate other skin conditions like rosacea or acne, causing flareups and breakouts.</p>
<p><strong>After Quitting: </strong>By replacing alcoholic drinks with plenty of water, you are allowing your skin to rehydrate and flush out toxins through urine and sweat. Your skin will regain its natural, healthy glow as you replenish the necessary vitamins and minerals lost from active addiction.</p>
<h2>3. Your Hair Will Grow</h2>
<p><strong>While Drinking:</strong> When alcohol dehydrates your body, it also dehydrates your hair. The lack of moisture causes thinning, hair loss, and dandruff on the scalp.  Hair shedding is compounded by alcohol triggering increased production of cortisol and the hormone estrogen.</p>
<p>Alcohol also inhibits nutrient absorption by harming the lining of your digestive system over time, damaging your intestines until they can’t transfer nutrients to the blood. Without proper protein, the production of keratin slows; this protective agent bonds hair cells together and your hair becomes prone to split ends and breakage. Similarly, zinc and folic acid, which are essential for hair growth, aren’t soaked up by your follicles.</p>
<p><strong>After Quitting:</strong> Your hair will regain its former strength as your body begins to repair itself from the effects of alcohol. The rate your hair grows will increase, and you’ll notice the change from hair loss to fuller, shinier locks.</p>
<p>Leaving alcohol behind and pursuing sobriety brings favorable changes to your appearance that you might not have anticipated. As you start to look good, you’ll feel good about yourself, and when you look in the mirror, you’ll see the old you again. <a href="https://mountainside.com/blog/alcohol/3-ways-your-appearance-changes-when-you-quit-drinking/" target="_blank" rel="noopener">source</a></p>
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<h1><em><span style="color: #3366ff;">&#8216;I Gave Up Alcohol a Year Ago—I Feel 10 Years Younger&#8217;</span></em></h1>
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<p><img loading="lazy" decoding="async" class="alignnone wp-image-17840" src="https://goodshepherdmedia.net/wp-content/uploads/2024/05/sam-walsh-gave-alcohol.png" alt="" width="709" height="532" srcset="https://goodshepherdmedia.net/wp-content/uploads/2024/05/sam-walsh-gave-alcohol.png 1600w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/sam-walsh-gave-alcohol-400x300.png 400w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/sam-walsh-gave-alcohol-1024x768.png 1024w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/sam-walsh-gave-alcohol-768x576.png 768w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/sam-walsh-gave-alcohol-1536x1152.png 1536w" sizes="(max-width: 709px) 100vw, 709px" /></p>
<p>I come from a family of drinkers so I grew up around alcohol. Whether we were celebrating or commiserating, alcohol was always involved. My paternal grandfather was actually born in a pub and named after it.</p>
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<p>From about the age of 15, I started experimenting with drinking alcohol at local parks with friends. The first time I drank when I was out was at a local youth disco. We probably didn&#8217;t even drink that much and it wasn&#8217;t a late night, but we got very drunk and an on-site ambulance service had to tend to us. But you only remember the fun parts, so it went on from there.</p>
<p>I&#8217;m 45 now, so my generation grew up in the &#8217;80s and &#8217;90s, during the rave scene in the U.K. All the people I hung out with drank. We&#8217;d go to bars and clubs and we had some really good times but it was just a given that you drank. I never really questioned it.</p>
<p>I got into a cycle of drinking every weekend and recovering at the start of the week. Then mid week would arrive and I would start having a few drinks in the evenings, waiting for the weekend to come. That went on for years. <a href="https://www.newsweek.com/quit-alcohol-life-transformed-1629761" target="_blank" rel="noopener">source</a></p>
<blockquote>
<h1><em><span style="color: #339966;">&#8216;I Quit Alcohol Four Years Ago—My Life Changed Completely&#8217;</span></em></h1>
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<p><img loading="lazy" decoding="async" class="alignnone size-full wp-image-17841" src="https://goodshepherdmedia.net/wp-content/uploads/2024/05/kenny-dunns-journey-quitting-alcohol.jpg" alt="" width="2000" height="1276" srcset="https://goodshepherdmedia.net/wp-content/uploads/2024/05/kenny-dunns-journey-quitting-alcohol.jpg 2000w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/kenny-dunns-journey-quitting-alcohol-400x255.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/kenny-dunns-journey-quitting-alcohol-1024x653.jpg 1024w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/kenny-dunns-journey-quitting-alcohol-768x490.jpg 768w, https://goodshepherdmedia.net/wp-content/uploads/2024/05/kenny-dunns-journey-quitting-alcohol-1536x980.jpg 1536w" sizes="(max-width: 2000px) 100vw, 2000px" /></p>
<p>By the time I was 34 years old, I was getting up every day and drinking alcohol. I knew where I could buy the cheapest hard liquor with the highest percentage of alcohol and no matter where I went, I usually had a mini bottle or two of liquor in my pocket.</p>
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<div id="google_ads_iframe_/43459271,22541732127/newsweek/inarticle1_0__container__">The same year—2016—I was driving home from a date with my wife one night when she asked for my coat to use as a blanket. When I realized I had mini bottles of liquor in the pockets, I selfishly told her I wanted my coat back for myself, just so I could hide the alcohol from her and so she wouldn&#8217;t realize I was driving while likely over the limit. At that time, I also always drank the moment I got home from work. Sometimes I couldn&#8217;t wait and I drank on the way home and I would be drunk when I arrived. My life was an absolute train wreck.</div>
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<p>Growing up in Vancouver, alcohol was always a fixture in my home. But though my parents both drank, they weren&#8217;t alcoholics and I only started drinking during senior year in high school as a way to socialize. In college, and throughout my 20s, I only ever consumed two or three drinks at a time; I could take it or leave it. I didn&#8217;t consider my drinking to be problematic, although I suspect a doctor may tell you differently.</p>
<p>I had also been an obese child and then struggled with my weight my whole life. In 2012, at 30 years old and nearly 350lbs, I had gastric bypass surgery. In less than a year I lost 190lbs. The surgery meant that alcohol was digested differently, it was sort of like drinking on an empty stomach. Soon, I began to notice that my relationship with alcohol had changed. I regularly needed to quench an absolutely uncontrollable thirst for alcohol; I wanted to drink until I was sick or blacked out.</p>
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<div id="teads0" class="teads-player">I wasn&#8217;t drinking to escape any real emotional trauma, despite having been through a lot. My relationship with alcohol just got seriously out of control. It was like a switch had been flipped.</div>
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<div>I would tell my wife that something wasn&#8217;t right and stop drinking for a month or two. I even had one stretch of sobriety that lasted 14 months; I felt I&#8217;d taken care of the problem. But when I drank after that, even though I would swear to myself that I would only have one or two, I would end up having 12 to 24 alcoholic drinks a night in secret.</div>
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<p>Sometimes I would buy wine in a box, decant it into a litre sized water bottle in the garage or bathroom and slug that down quickly. My behaviour became erratic and I wasn&#8217;t able to meet my commitments at work. When I was drunk, I would look in the mirror and say, &#8220;How did I get like this?&#8221; and then the next might I would be drunk again.</p>
<p>I was also an emotional wreck. I had trouble relating to my family and I would get angry very easily. I was irritable, restless and I didn&#8217;t sleep well. I got to a point where I knew that if I didn&#8217;t reach out for help, I would be a dead man.</p>
<p>On November 2, 2016, I had a week of vacation starting and I bought myself a case of 24 beers. I was going to ration them out and have three or four beers a night. I put my son to bed at 8pm and cracked open my first beer. By 11pm I had finished 19 of them. Something inside of me said: &#8220;Kenny, your life is no longer manageable.&#8221; It was true.</p>
<p>I reached out to a friend of mine who I knew was in recovery from alcoholism, something I had never done before. The next morning she took me to a meeting for addicts. I knew I was home amongst those people because each of them told a story that could have been mine. I finally realized then: I&#8217;m an alcoholic.</p>
<p>In the 12 Step program I learned that stopping on my own is not something that I have the physical or emotional capability of doing. That program worked for me, but if something else works for other people, that&#8217;s great. There are many ways to get sober and 12 Step is just one of them. However, it was foolish of me to stop drinking on my own without consulting a doctor.</p>
<p>In that first week I had to call a complete stranger, someone who had been through the program, and ask them to be my sponsor. That was hell. But that guy told me to call him and go to a meeting every day. When I said that was too much, I remember he replied, &#8220;well, you drank every day.&#8221; I had no rebuttal.</p>
<p>For the first 30 days I was on what is called the &#8220;pink cloud.&#8221; I was very happy; it was like coming out of a bad relationship. The &#8220;pink cloud&#8221; ended when my sponsor said that I had to clean up the mess I had made of my life and all the people that I had harmed. That was when it got difficult and I started having doubts about recovery. You have to address what led you down the path to wanting to alter your state in the first place. I just wanted my life back, but instead I was encouraged to fix the old one.</p>
<p>It took me about 10 months to get through all 12 Steps and eventually I chose to put my trust in a higher power, something I was taught by the program, though it doesn&#8217;t have to be God.</p>
<p>I realized that I had been angry about many things in my life, all the way from childhood. Part of the program is recognizing that and letting it go. Then you have to make a list of all the people that you&#8217;ve harmed and make amends to them. It&#8217;s not just apologizing, you actually have to mend the situation.</p>
<p>When I was drinking I would go onto social media every night and lash out at people. I was angry, spiteful and resentful to my friends and peers, and sometimes strangers. I had a lot of situations that I needed to make right.</p>
<p>I had also stolen from people and I had to pay them back. That was hard. I&#8217;m a family man so it was difficult for me to accept that I had stolen whilst under the influence of alcohol, or in order to become under the influence of alcohol.</p>
<p>So, life as a sober person was very difficult at the beginning. Although my wife doesn&#8217;t drink, I couldn&#8217;t go to places where alcohol was served and I became a bit of an introvert. At our family Christmas in 2016, I noticed there was no alcohol and a few hours in I asked my father why they weren&#8217;t drinking. He told me not to worry. I realized my family had collectively decided to abstain from alcohol for my sake. It was very emotional and it absolutely meant the world to me. Now, I don&#8217;t have an issue being around alcohol, but it was hard for a while. <a href="https://www.newsweek.com/i-quit-alcohol-life-changed-completely-1597089" target="_blank" rel="noopener">source</a></p>
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		<title>Brain Anatomy and How the Brain Works</title>
		<link>https://goodshepherdmedia.net/brain-anatomy-and-how-the-brain-works/</link>
		
		<dc:creator><![CDATA[The Truth News]]></dc:creator>
		<pubDate>Sat, 18 Mar 2023 08:47:39 +0000</pubDate>
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					<description><![CDATA[Brain Anatomy and How the Brain Works What is the brain? The brain is a complex organ that controls thought, memory, emotion, touch, motor skills, vision, breathing, temperature, hunger and every process that regulates our body. Together, the brain and spinal cord that extends from it make up the central nervous system, or CNS. What [&#8230;]]]></description>
										<content:encoded><![CDATA[<h1 id="introduction" class="main-content__title " style="text-align: center;" data-anchor="Introduction">Brain Anatomy and How the Brain Works</h1>
<h2>What is the brain?</h2>
<p>The brain is a complex organ that controls thought, memory, emotion, touch, motor skills, vision, breathing, temperature, hunger and every process that regulates our body. Together, the brain and spinal cord that extends from it make up the central nervous system, or CNS.</p>
<h2>What is the brain made of?</h2>
<p>Weighing about 3 pounds in the average adult, the brain is about 60% fat. The remaining 40% is a combination of water, protein, carbohydrates and salts. The brain itself is a not a muscle. It contains blood vessels and nerves, including neurons and glial cells.</p>
<h3>What is the gray matter and white matter?</h3>
<p>Gray and white matter are two different regions of the central nervous system. In the brain, gray matter refers to the darker, outer portion, while white matter describes the lighter, inner section underneath. In the spinal cord, this order is reversed: The white matter is on the outside, and the gray matter sits within.</p>
<p><img loading="lazy" decoding="async" class="alignnone size-full wp-image-12604" src="https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-spine-gray-and-white-matter.jpg" alt="" width="1858" height="522" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-spine-gray-and-white-matter.jpg 1858w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-spine-gray-and-white-matter-400x112.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-spine-gray-and-white-matter-1024x288.jpg 1024w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-spine-gray-and-white-matter-768x216.jpg 768w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-spine-gray-and-white-matter-1536x432.jpg 1536w" sizes="(max-width: 1858px) 100vw, 1858px" /></p>
<p>Gray matter is primarily composed of neuron somas (the round central cell bodies), and white matter is mostly made of axons (the long stems that connects neurons together) wrapped in myelin (a protective coating). The different composition of neuron parts is why the two appear as separate shades on certain scans.</p>
<p><img loading="lazy" decoding="async" class="alignnone size-full wp-image-12603" src="https://goodshepherdmedia.net/wp-content/uploads/2023/03/neuron-anatomy-diagram.jpg" alt="" width="1130" height="717" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/03/neuron-anatomy-diagram.jpg 1130w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/neuron-anatomy-diagram-400x254.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/neuron-anatomy-diagram-1024x650.jpg 1024w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/neuron-anatomy-diagram-768x487.jpg 768w" sizes="(max-width: 1130px) 100vw, 1130px" /></p>
<p>Each region serves a different role. Gray matter is primarily responsible for processing and interpreting information, while white matter transmits that information to other parts of the nervous system.</p>
<h2>How does the brain work?</h2>
<p>The brain sends and receives chemical and electrical signals throughout the body. Different signals control different processes, and your brain interprets each. Some make you feel tired, for example, while others make you feel pain.</p>
<p>Some messages are kept within the brain, while others are relayed through the spine and across the body’s vast network of nerves to distant extremities. To do this, the central nervous system relies on billions of neurons (nerve cells).</p>
<h2>Main Parts of the Brain and Their Functions</h2>
<p>At a high level, the brain can be divided into the cerebrum, brainstem and cerebellum.</p>
<p><img loading="lazy" decoding="async" class="alignnone size-full wp-image-12602" src="https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-main-parts.png" alt="" width="800" height="800" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-main-parts.png 800w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-main-parts-400x400.png 400w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-main-parts-150x150.png 150w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-main-parts-768x768.png 768w" sizes="(max-width: 800px) 100vw, 800px" /></p>
<h3>Cerebrum</h3>
<p>The cerebrum (front of brain) comprises gray matter (the cerebral cortex) and white matter at its center. The largest part of the brain, the cerebrum initiates and coordinates movement and regulates temperature. Other areas of the cerebrum enable speech, judgment, thinking and reasoning, problem-solving, emotions and learning. Other functions relate to vision, hearing, touch and other senses.</p>
<h4>Cerebral Cortex</h4>
<p>Cortex is Latin for “bark,” and describes the outer gray matter covering of the cerebrum. The cortex has a large surface area due to its folds, and comprises about half of the brain’s weight.</p>
<p>The cerebral cortex is divided into two halves, or hemispheres. It is covered with ridges (gyri) and folds (sulci). The two halves join at a large, deep sulcus (the interhemispheric fissure, AKA the medial longitudinal fissure) that runs from the front of the head to the back. The right hemisphere controls the left side of the body, and the left half controls the right side of the body. The two halves communicate with one another through a large, C-shaped structure of white matter and nerve pathways called the corpus callosum. The corpus callosum is in the center of the cerebrum.</p>
<h3>Brainstem</h3>
<p>The brainstem (middle of brain) connects the cerebrum with the spinal cord. The brainstem includes the midbrain, the pons and the medulla.</p>
<ul>
<li><strong>Midbrain.</strong> The midbrain (or mesencephalon) is a very complex structure with a range of different neuron clusters (nuclei and colliculi), neural pathways and other structures. These features facilitate various functions, from hearing and movement to calculating responses and environmental changes. The midbrain also contains the substantia nigra, an area affected by Parkinson’s disease that is rich in dopamine neurons and part of the basal ganglia, which enables movement and coordination.</li>
<li><strong>Pons. </strong>The pons is the origin for four of the 12 cranial nerves, which enable a range of activities such as tear production, chewing, blinking, focusing vision, balance, hearing and facial expression. Named for the Latin word for “bridge,” the pons is the connection between the midbrain and the medulla.</li>
<li><strong>Medulla. </strong>At the bottom of the brainstem, the medulla is where the brain meets the spinal cord. The medulla is essential to survival. Functions of the medulla regulate many bodily activities, including heart rhythm, breathing, blood flow, and oxygen and carbon dioxide levels. The medulla produces reflexive activities such as sneezing, vomiting, coughing and swallowing.</li>
</ul>
<p>The <strong>spinal cord</strong> extends from the bottom of the medulla and through a large opening in the bottom of the skull. Supported by the vertebrae, the spinal cord carries messages to and from the brain and the rest of the body.</p>
<h3>Cerebellum</h3>
<p>The cerebellum (“little brain”) is a fist-sized portion of the brain located at the back of the head, below the temporal and occipital lobes and above the brainstem. Like the cerebral cortex, it has two hemispheres. The outer portion contains neurons, and the inner area communicates with the cerebral cortex. Its function is to coordinate voluntary muscle movements and to maintain posture, balance and equilibrium. New studies are exploring the cerebellum’s roles in thought, emotions and social behavior, as well as its possible involvement in addiction, autism and schizophrenia.</p>
<h3>Brain Coverings: Meninges</h3>
<p>Three layers of protective covering called <strong>meninges</strong> surround the brain and the spinal cord.</p>
<ul>
<li>The outermost layer, the <strong>dura mater</strong>, is thick and tough. It includes two layers: The periosteal layer of the dura mater lines the inner dome of the skull (cranium) and the meningeal layer is below that. Spaces between the layers allow for the passage of veins and arteries that supply blood flow to the brain.</li>
<li>The <strong>arachnoid </strong>mater is a thin, weblike layer of connective tissue that does not contain nerves or blood vessels. Below the arachnoid mater is the cerebrospinal fluid, or CSF. This fluid cushions the entire central nervous system (brain and spinal cord) and continually circulates around these structures to remove impurities.</li>
<li>The <strong>pia mater</strong> is a thin membrane that hugs the surface of the brain and follows its contours. The pia mater is rich with veins and arteries.</li>
</ul>
<p><img loading="lazy" decoding="async" class="alignnone size-full wp-image-12601" src="https://goodshepherdmedia.net/wp-content/uploads/2023/03/meninges-layers.jpg" alt="" width="1400" height="1232" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/03/meninges-layers.jpg 1400w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/meninges-layers-400x352.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/meninges-layers-1024x901.jpg 1024w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/meninges-layers-768x676.jpg 768w" sizes="(max-width: 1400px) 100vw, 1400px" /></p>
<h2>Lobes of the Brain and What They Control</h2>
<p>Each brain hemisphere (parts of the cerebrum) has four sections, called lobes: frontal, parietal, temporal and occipital. Each lobe controls specific functions.</p>
<p><img loading="lazy" decoding="async" class="alignnone size-full wp-image-12600" src="https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-lobes-anatomy.jpg" alt="" width="1400" height="1050" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-lobes-anatomy.jpg 1400w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-lobes-anatomy-400x300.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-lobes-anatomy-1024x768.jpg 1024w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-lobes-anatomy-768x576.jpg 768w" sizes="(max-width: 1400px) 100vw, 1400px" /></p>
<ul>
<li><strong>Frontal lobe.</strong> The largest lobe of the brain, located in the front of the head, the frontal lobe is involved in personality characteristics, decision-making and movement. Recognition of smell usually involves parts of the frontal lobe. The frontal lobe contains Broca’s area, which is associated with speech ability.</li>
<li><strong>Parietal lobe. </strong>The middle part of the brain, the parietal lobe helps a person identify objects and understand spatial relationships (where one’s body is compared with objects around the person). The parietal lobe is also involved in interpreting pain and touch in the body. The parietal lobe houses Wernicke’s area, which helps the brain understand spoken language.</li>
<li><strong>Occipital lobe.</strong> The occipital lobe is the back part of the brain that is involved with vision.</li>
<li><strong>Temporal lobe.</strong> The sides of the brain, temporal lobes are involved in short-term memory, speech, musical rhythm and some degree of smell recognition.</li>
</ul>
<h2>Deeper Structures Within the Brain</h2>
<h3>Pituitary Gland</h3>
<p>Sometimes called the “master gland,” the pituitary gland is a pea-sized structure found deep in the brain behind the bridge of the nose. The pituitary gland governs the function of other glands in the body, regulating the flow of hormones from the thyroid, adrenals, ovaries and testicles. It receives chemical signals from the hypothalamus through its stalk and blood supply.</p>
<h3>Hypothalamus</h3>
<p>The hypothalamus is located above the pituitary gland and sends it chemical messages that control its function. It regulates body temperature, synchronizes sleep patterns, controls hunger and thirst and also plays a role in some aspects of memory and emotion.</p>
<h3>Amygdala</h3>
<p>Small, almond-shaped structures, an amygdala is located under each half (hemisphere) of the brain. Included in the limbic system, the amygdalae regulate emotion and memory and are associated with the brain’s reward system, stress, and the “fight or flight” response when someone perceives a threat.</p>
<h3>Hippocampus</h3>
<p>A curved seahorse-shaped organ on the underside of each temporal lobe, the hippocampus is part of a larger structure called the hippocampal formation. It supports memory, learning, navigation and perception of space. It receives information from the cerebral cortex and may play a role in Alzheimer’s disease.</p>
<h3>Pineal Gland</h3>
<p>The pineal gland is located deep in the brain and attached by a stalk to the top of the third ventricle. The pineal gland responds to light and dark and secretes melatonin, which regulates circadian rhythms and the sleep-wake cycle.</p>
<h3>Ventricles and Cerebrospinal Fluid</h3>
<p>Deep in the brain are four open areas with passageways between them. They also open into the central spinal canal and the area beneath arachnoid layer of the meninges.</p>
<p>The ventricles manufacture <strong>cerebrospinal fluid</strong>, or CSF, a watery fluid that circulates in and around the ventricles and the spinal cord, and between the meninges. CSF surrounds and cushions the spinal cord and brain, washes out waste and impurities, and delivers nutrients.</p>
<p><img loading="lazy" decoding="async" class="alignnone size-full wp-image-12599" src="https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-cross-section-deeper-structure.jpg" alt="" width="1400" height="1413" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-cross-section-deeper-structure.jpg 1400w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-cross-section-deeper-structure-396x400.jpg 396w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-cross-section-deeper-structure-1015x1024.jpg 1015w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-cross-section-deeper-structure-150x150.jpg 150w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-cross-section-deeper-structure-768x775.jpg 768w" sizes="(max-width: 1400px) 100vw, 1400px" /></p>
<h2>Blood Supply to the Brain</h2>
<p>Two sets of blood vessels supply blood and oxygen to the brain: the <strong>vertebral arteries</strong> and the <strong>carotid arteries.</strong></p>
<p>The external carotid arteries extend up the sides of your neck, and are where you can feel your pulse when you touch the area with your fingertips. The internal carotid arteries branch into the skull and circulate blood to the front part of the brain.</p>
<p>The vertebral arteries follow the spinal column into the skull, where they join together at the brainstem and form the <strong>basilar artery</strong>, which supplies blood to the rear portions of the brain.</p>
<p>The <strong>circle of Willis</strong>, a loop of blood vessels near the bottom of the brain that connects major arteries, circulates blood from the front of the brain to the back and helps the arterial systems communicate with one another.</p>
<p><img loading="lazy" decoding="async" class="alignnone size-full wp-image-12598" src="https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-circulatory-system.jpg" alt="" width="1400" height="1000" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-circulatory-system.jpg 1400w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-circulatory-system-400x286.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-circulatory-system-1024x731.jpg 1024w, https://goodshepherdmedia.net/wp-content/uploads/2023/03/brain-circulatory-system-768x549.jpg 768w" sizes="(max-width: 1400px) 100vw, 1400px" /></p>
<h2>Cranial Nerves</h2>
<p>Inside the cranium (the dome of the skull), there are 12 nerves, called cranial nerves:</p>
<ul>
<li>Cranial nerve 1: The first is the <strong>olfactory nerve, </strong>which allows for your sense of smell.</li>
<li>Cranial nerve 2: The <strong>optic nerve</strong> governs eyesight.</li>
<li>Cranial nerve 3: The <strong>oculomotor nerve</strong> controls pupil response and other motions of the eye, and branches out from the area in the brainstem where the midbrain meets the pons.</li>
<li>Cranial nerve 4: The <strong>trochlear nerve</strong> controls muscles in the eye. It emerges from the back of the midbrain part of the brainstem.</li>
<li>Cranial nerve 5: The <strong>trigeminal nerve</strong> is the largest and most complex of the cranial nerves, with both sensory and motor function. It originates from the pons and conveys sensation from the scalp, teeth, jaw, sinuses, parts of the mouth and face to the brain, allows the function of chewing muscles, and much more.</li>
<li>Cranial nerve 6: The <strong>abducens nerve</strong> innervates some of the muscles in the eye.</li>
<li>Cranial nerve 7: The <strong>facial nerve</strong> supports face movement, taste, glandular and other functions.</li>
<li>Cranial nerve 8: The <strong>vestibulocochlear nerve</strong> facilitates balance and hearing.</li>
<li>Cranial nerve 9: The <strong>glossopharyngeal nerve</strong> allows taste, ear and throat movement, and has many more functions.</li>
<li>Cranial nerve 10: The <strong>vagus nerve</strong> allows sensation around the ear and the digestive system and controls motor activity in the heart, throat and digestive system.</li>
<li>Cranial nerve 11: The <strong>accessory nerve</strong> innervates specific muscles in the head, neck and shoulder.</li>
<li>Cranial nerve 12: The <strong>hypoglossal nerve</strong> supplies motor activity to the tongue.</li>
</ul>
<p>The first two nerves originate in the cerebrum, and the remaining 10 cranial nerves emerge from the brainstem, which has three parts: the midbrain, the pons and the medulla.</p>
<p><a href="https://www.hopkinsmedicine.org/health/conditions-and-diseases/anatomy-of-the-brain" target="_blank" rel="noopener">source</a></p>
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		<title>The Health Benefits of Being Sober</title>
		<link>https://goodshepherdmedia.net/the-health-benefits-of-being-sober/</link>
		
		<dc:creator><![CDATA[The Truth News]]></dc:creator>
		<pubDate>Sun, 19 Feb 2023 12:20:25 +0000</pubDate>
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					<description><![CDATA[The Health Benefits of Being Sober From healthier-looking skin to increased mental stability, here are the health benefits of sobriety. Robert Downey Jr. accepted the American Cinematheque award over the weekend, he chose his friend Mel Gibson to present the honor.  &#8220;When people get sober they sleep better, have more energy, and can think more [&#8230;]]]></description>
										<content:encoded><![CDATA[<h1 style="text-align: center;">The Health Benefits of Being Sober</h1>
<blockquote>
<h3 style="text-align: center;"><span style="color: #0000ff;"><em>From healthier-looking skin to increased mental stability, here are the health benefits of sobriety.</em></span></h3>
<p><span style="color: #0000ff;"><em>Robert Downey Jr. accepted the American Cinematheque award over the weekend, he chose his friend Mel Gibson to present the honor. </em></span></p>
<div style="width: 640px;" class="wp-video"><video class="wp-video-shortcode" id="video-12054-1" width="640" height="1138" loop autoplay preload="metadata" controls="controls"><source type="video/mp4" src="https://goodshepherdmedia.net/wp-content/uploads/2023/02/Robert-Downey-Jr.-pays-tribute-to-Mel-Gibson-in-EPIC-speech-about-forgiveness.mp4?_=1" /><a href="https://goodshepherdmedia.net/wp-content/uploads/2023/02/Robert-Downey-Jr.-pays-tribute-to-Mel-Gibson-in-EPIC-speech-about-forgiveness.mp4">https://goodshepherdmedia.net/wp-content/uploads/2023/02/Robert-Downey-Jr.-pays-tribute-to-Mel-Gibson-in-EPIC-speech-about-forgiveness.mp4</a></video></div></blockquote>
<p>&#8220;When people get sober they sleep better, have more energy, and can think more clearly,&#8221; says Dr. Dr. Brian Wind, Ph.D &#8220;Best of all, sober people aren&#8217;t damaging nearly every part of their bodies on a daily basis and aren&#8217;t waking up with hangovers or withdrawals.&#8221;</p>
<p>Sobriety isn&#8217;t and won&#8217;t be easy. Some benefits will be noticeable immediately, while others take time. If you have a substance abuse problem you may initially go through physical symptoms of withdrawal, but the benefits of sobriety certainly outweigh any potentially negative effects of withdrawal.</p>
<h2>Physical benefits</h2>
<ul>
<li>Increased general health</li>
<li>Improved mental clarity (focus, critical thinking, memory)</li>
<li>Longer and deeper sleep</li>
<li>Increased energy</li>
<li>Healthier skin and complexion</li>
<li>Decreased risk of long-term health issues including cancer</li>
<li>Better weight management and eating habits</li>
</ul>
<p>&#8220;The before and after photos depicting recovery from substance use are very compelling,&#8221; says Dr. Lori Ryland&#8221;As substance use reduces, you begin taking better care of yourself by eating healthy instead of using, better activity, and often better healthcare adherence in comparison to periods of use.&#8221;</p>
<p>While sobriety will have a positive effect on your physical well-being, the benefits are equally as important to your emotional state. Emotional stability—which affects everything from your relationships, motivation, and general mood—will vastly improve.</p>
<p>&#8220;In general, an individual is significantly more emotionally stable and balanced when sober than during an active addiction,&#8221; says Dr. Dean Drosnes,</p>
<h2>Emotional benefits</h2>
<ul>
<li>Increased confidence</li>
<li>Emotional stability</li>
<li>Better overall well-being</li>
<li>Improved relationships</li>
<li>More motivation</li>
<li>Depression relief</li>
<li>Anxiety relief</li>
</ul>
<p>the benefits of sobriety are manifested in several ways, including: mental(<a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#1">1</a>) and physical health(<a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#2">2</a>), markedly improved relationships with friends and family(<a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#3">3</a>), as well as in your finances and career(<a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#4">4</a>, <a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#5">5</a>).</p>
<p>Even if you are not experiencing these negative outcomes, heavy drinking can be detrimental both short and long-term. Getting sober may help to reverse or even eliminate the negative impact that alcohol may have on your mental and physical health, personal relationships, as well as your career or financial situation.</p>
<p><img loading="lazy" decoding="async" class="size-full wp-image-13029 aligncenter" src="https://goodshepherdmedia.net/wp-content/uploads/2023/02/f91eba13baaf6663c4faa5caa75ffaab.jpg" alt="" width="564" height="564" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/02/f91eba13baaf6663c4faa5caa75ffaab.jpg 564w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/f91eba13baaf6663c4faa5caa75ffaab-400x400.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/f91eba13baaf6663c4faa5caa75ffaab-150x150.jpg 150w" sizes="(max-width: 564px) 100vw, 564px" /></p>
<hr />
<h2>The Benefits of Being Sober</h2>
<h3>Physical Health</h3>
<div class="wp-block-image">
<figure class="aligncenter size-large"><img loading="lazy" decoding="async" class="alignnone size-full wp-image-12055" src="https://goodshepherdmedia.net/wp-content/uploads/2023/02/mental-and-physical-effects-of-alcoholism.jpg" alt="" width="998" height="685" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/02/mental-and-physical-effects-of-alcoholism.jpg 998w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/mental-and-physical-effects-of-alcoholism-400x275.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/mental-and-physical-effects-of-alcoholism-768x527.jpg 768w" sizes="(max-width: 998px) 100vw, 998px" /></figure>
</div>
<p>Heavy alcohol use has been linked with a vast amount of negative outcomes, including(<a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#6">6</a>):</p>
<ul data-slot-rendered-content="true">
<li>Alcoholic cirrhosis of the liver</li>
<li>Alcohol induced acute/chronic pancreatitis</li>
<li>Alcoholic myophathy and cardiomyophathy</li>
<li>Increased rates of certain cancers like breast, stomach, oral, and colon</li>
<li>Degeneration of the nervous system (decreased ability to fight infection)</li>
</ul>
<p>Chronic alcohol use has also been attributed to erectile dysfunction as well as other sexual dysfunctions(<a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#7">7</a>). Sexual dysfunction was significantly associated with duration and severity of alcohol dependence as well as the amount of alcohol consumed per day.</p>
<p>Upon stopping the intake of alcohol, these physical consequences may subside. However, when a heavy drinker stops they may experience(<a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#8">8</a>):</p>
<ul>
<li>Weight loss</li>
<li>Improved pancreatic function</li>
<li>Reduced risk of cancer</li>
<li>Lower blood pressure</li>
</ul>
<h3>Mental Health</h3>
<p>Heavy alcohol consumption has been associated with negative impacts on mental health. This is primarily due to blocking chemical signals between brain cells (neurons)(<a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#9">9</a>). For instance, alcohol consumption results in slurred speech, slowed reflexes, poor memory, and impulsive behavior.</p>
<p>Due to heavy alcohol consumption the brain can adapt to these blocked pathways. When alcohol leaves the system it will continue to over-activate neurotransmitters that can result in damage to brain cells(<a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#10">10</a>, <a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#11">11</a>, <a class="rank-math-link" href="https://www.inspireusafoundation.org/benefits-of-being-sober/#12">12</a>).</p>
<p>Alcohol use can also negatively impact sleep patterns. Similar to other sleep medications, the sedative or sleep inducing effects of alcohol are quickly adapted to which only leads to further sleep related problems.</p>
<p>Wile it can be hard to say whether alcohol plays a significant role in mental health issues such as anxiety, psychosis, or depression. Through the transitive property, we know that if these issues subside when the person stops drinking, it&#8217;s logical to assume alcohol aggravates those conditions.</p>
<h3>Relationships with Family and Friends</h3>
<p>Alcoholism typically has a negative impact on personal relationships with friends and family.</p>
<p>Studies show that higher partner violence is associated with heavy alcohol consumption. Abstaining from alcohol has the opposite effect and may result in less conflicts and domestic violence.</p>
<p>Alcohol can also affect a person&#8217;s attachment to others (partner, spouse, children, friends, and family). People who have attachment issues typically are less trusting, show signs of fear, and will isolate and detach themselves.</p>
<h3>Career and Financial Situation</h3>
<p>Most people who drink alcohol do not think about the impact of alcohol on their financial well-being. People who abuse alcohol are more likely to miss work and have conflict amongst co-workers and management.</p>
<p>Going to and from work may end up resulting in a DUI only adding more financial burden (bail, court fines, attorney, public transportation cost, etc).</p>
<h3>Final Thoughts</h3>
<p>Apart from the purported &#8220;holistic&#8221; benefits of being sober, there are fact-based reasons for why sobriety is beneficial. Including for your mental and physical health, personal relationships, and for your career/financial situation.</p>
<hr />
<ol>
<li><strong>Your life becomes less chaotic </strong>You don’t have to live in constant turmoil anymore because you’re not worried about getting money, getting drugs or alcohol, and then lying or manipulating to cover up your behaviors. You finally get a chance to sit still and relax.</li>
<li><strong>You sleep better </strong>When you suffer from <strong>Alcohol abuse is disruptive to sleeping patterns</strong> because it suppresses sleep, not permitting a restorative, good nights rest. Though you may have trouble falling asleep when you first get sober, you will soon sleep peacefully through the night and feel more rested the next day.</li>
<li><strong>You feel healthier </strong>Substance abuse has profound <strong>effects on the body</strong>. In sobriety, you aren’t putting toxic chemicals in your body, so you will actually have more energy and feel more alert and focused! Not to mention the fact that your internal organs get to take a break from working overtime to process the drugs and alcohol. More Energy, Alcohol is a depressant, which makes you feel tired and slow. Without the constant effect of alcohol on your body, you have a lot more energy to work with. This energy can lead to healthier choices.</li>
<li><strong>You look better </strong>Do you have sunken in cheeks, red patches, or bad acne? Good news – in sobriety, your skin actually improves! Without nasty, toxic chemicals in your body, your complexion will improve tremendously and you will gain weight back to your face, making you look beautiful and healthy again!  Better Skin, When it comes to improving physical health, better skin is one of the most noticeable changes in most people. People in recovery have a more radiant complexion than before. Their skin becomes clearer — and, in many cases, cleaner due to improved hygiene. Within the first six months of sobriety, most people undergo observable and positive changes in their skin.</li>
<li><strong>Your memory improves </strong>We all have nights we don’t remember while in addiction, but <strong>shortly after detox</strong>, your memory will rapidly begin to improve. No more worrying about what you did last night – your memory will become sharp and as good as new!</li>
<li><strong>Your mental health improves (no more brain fog) </strong>Sleep, diet, and overall health are directly correlated with the status of your mental health. As your lifestyle improves, you will find your emotions more stable and manageable. You will find yourself having less mood swings along with increased happiness. Alcohol is incredibly inflammatory. The long and short-term impact of alcohol on your brain is extensive. I won’t go into detail here because I’ve written about it before, but if you can’t engage intellectually with the world like you used to, you’re forgetting more things or struggling to focus, there is good news for you, my friend! Your brain can heal. You can get your mental faculties back! This one happened for me relatively early on, and that’s WITH pregnancy brain. It is an incredible feeling to have that fog lift. You quite literally feel like a brand new person. The ability to think, read a book, engage in an intelligent conversation, actually have IDEAS again, and not just loop terrible thoughts on autopilot in your brain is liberating. <strong>It’s one of the best benefits of sobriety I’ve experienced.</strong></li>
<li><strong>You worry less </strong>When you are sober and doing the right thing, the worry of getting in trouble with others or getting caught by the cops disappears. You’re sober, you have a job, you are being honest with others, you have a roof over your head, you aren’t worried about going into withdrawals – what’s there to worry about anymore?</li>
<li><strong>You actually have money </strong>When you aren’t spending every penny earned on drugs or alcohol, you will be surprised how quickly your savings adds up! It is a wonderful feeling not to worry about living paycheck to paycheck and being able to have savings for emergencies.</li>
<li><strong>You get to be a part of your family </strong>Regardless of the harms you have done, <strong>your family loves you</strong> and will forgive you in time. It is a great feeling to be with family on holidays and special occasions without causing them to worry about your drug or alcohol use. They will be able to rely on you and trust you, and since you have money, you can even buy them gifts for their birthdays!</li>
<li><strong>You form deep connections with others </strong>Friendships made in sobriety are like no other. These friends understand exactly what you are going through because they have been there too. They will love and support you unconditionally. There is something about friendships in recovery that is magical.</li>
<li><strong>You gain long term rewards </strong>Hard work pays off. If you put in the work to be sober and happy, you will be sober and happy. You will be able to go to class and study for school in order to further your education. You will be capable of holding a job, allowing you to move up in your career. You will develop a profound appreciation for people, places, and things.</li>
<li><strong>You get to embark on new adventures </strong>You have the ability to try new things, travel to new places, and <strong>develop a passion for life</strong> after addiction. Since you will no longer rely on substances to survive each day, you will finally have the opportunity to thrive in life. There is nothing holding you back. Go climb that mountain, go snorkeling at a coral reef, go visit a foreign country! What are you waiting for?</li>
<li><strong>You grow spiritually </strong>Spiritual growth consists of removing obsolete or negative habits and thoughts from your life. <strong>Mindful meditation</strong> is a great way to grow spiritually because it relaxes your mind and aids in coping with feelings of anxiety and stress. It is a free, easy to do activity that promotes healing and spiritual growth by connecting your mind, body, and spirit. Sobriety brings so much peace into your life. It allows you to become more aware and present. You understand and connect with yourself better. When you’re sober, the entirety of who you are improves. Happiness is easy to come by when you’re doing good for yourself, looking better, feeling better, and functioning on a higher physical level.</li>
<li><strong>You find your purpose in life </strong>There is somebody out there who is hopeless and feels like they cannot stay sober. You may not know it at the time, but your story is the only story they will hear. Your experience, strength, and hope, is going to help somebody stay sober. You have the ability to <strong>change lives</strong>.</li>
<li><strong>You learn to love yourself </strong>By staying healthy, having new experiences, building relationships, and helping others, you will begin to truly love yourself. You will treat your body and mind with a gentle respect, as you have been blessed with a new, sober life. For many of us, we have spent too much time hating ourselves. Being able to love who we are, for all of our imperfections, is nothing short of a miraculous gift in sobriety.</li>
<li><strong>Less Stress </strong>People who abuse alcohol get to a point in their drinking where they cannot manage any emotion in a healthy way. Drinking is the solution to boredom, frustration, sadness, and extreme happiness. Additionally, research has shown that drinking any amount of alcohol chronically (including one drink per day) changes your Hypothalamic-Pituitary-Adrenal axis (HPA), which Maintains your physiological balance between what you do and don’t perceive as stressful. This leads to more cortisol released at baseline when you’re not drinking. Translation: alcohol increases your anxiety and stress levels even when not drinking. It was a horrible cycle of self-medicating my anxiety with alcohol which, in turn, only made my anxiety levels worse. I was stressed out all of the time and had no healthy coping mechanisms for that stress. Sobriety changed that. As a fair warning, sometimes alcohol withdrawal can have the opposite effect and make anxiety significantly worse, but it is temporary. It goes away, and you feel much more stable and clear-headed after the initial withdrawal period.</li>
<li><strong>Less Physical Pain </strong>Alcohol is incredibly inflammatory. it causes joint problems eventually speeding up arthritis and generally causing more pain in the joints.  It wreaks havoc with your gastrointestinal system and digestive system.  It will destroy your liver, heart, kidneys and pancreas! It will cause your blood pressure to be high and rapid pulse can develop. <span style="color: #ff0000;">PERMANENT HEART DAMAGE CAN OCCUR.</span></li>
<li><strong>Self Esteem will rise overtime  </strong>When you finally get over those first months of early sobriety, you’ll see that you’re not so bad after all. People who are successful with their sobriety find ways to keep themselves busy. It’s through that process that many people start to forgive themselves and see the value they can bring to the world. <strong>Every day you go without drinking boosts your self-esteem, even if you don’t notice. </strong>When you choose to go to the gym or take a cooking class, you’re signaling that you are open to seeing what else this life has to offer. The cumulative effects of all these new experiences and choices add up.</li>
<li><strong>Healthier realationships </strong>A lot of people feel lonely when they give up alcohol. When your entire social life has revolved around getting wasted, it’s normal to feel like there’s nothing to do. <strong>Re-evaluating your relationships with other people is part of the process. </strong>We all have to go through it, but the AMAZING thing is that you’ll end up with really powerful connections with the people you choose to keep around. You might think that emotionally unloading with your friends over wine and cookies makes you close or that your buddy holding your hair while you puked means something.</li>
<li><strong>Better Sleep Pattern </strong>Sobriety is your body at its most natural state, so when you’re sober, your body goes back into a more regular rhythm. Instead of drinking until the early morning hours, you now give yourself a chance to rest earlier and get quality sleep. The peace of mind that sobriety comes with also makes you less stressed and more able to get enough restful sleep at normal hours.</li>
<li><strong>Better Eating habbits </strong>Some people in recovery consider getting over addiction as their first step to living a much healthier lifestyle. Post-treatment, you may develop a consistent exercise routine to get your mind off drinking. Following a healthy diet is similar to this. They’re both excellent ways to improve your health and also things you can focus on to fill in the gaps left by addiction in your life. When you stop drinking, your body also becomes much less dehydrated. This lessens the chances of developing unhealthy food cravings. While eating healthier can help you stay sober, it’s also true that staying sober can help you eat healthier. For example, you can eat healthier because you have the energy to cook dishes instead of ordering fast food.<a href="https://www.webmd.com/connect-to-care/addiction-treatment-recovery/health-benefits-sobriety" target="_blank" rel="noopener">source</a> <a href="https://www.inspireusafoundation.org/benefits-of-being-sober/" target="_blank" rel="noopener">source</a> <a href="https://newdirections.co/benefits-staying-sober/" target="_blank" rel="noopener">source</a> <a href="https://www.midwestdetoxcenter.com/rehab-blog/7-impressive-health-benefits-of-sobriety/" target="_blank" rel="noopener">source</a></li>
</ol>
<h3 style="text-align: center;"><span style="color: #0000ff;"><a style="color: #0000ff;" href="https://goodshepherdmedia.net/the-health-benefits-of-being-sober/" target="_blank" rel="noopener">The Health Benefits of Being Sober</a></span></h3>
<h3 style="text-align: center;"><span style="color: #0000ff;"><a style="color: #0000ff;" href="https://goodshepherdmedia.net/the-importance-of-being-trustworthy/" target="_blank" rel="noopener">The Importance of Being Trustworthy</a></span></h3>
<h3 style="text-align: center;"><span style="color: #0000ff;"><a style="color: #0000ff;" href="https://goodshepherdmedia.net/why-is-hope-important-in-life-you-will-be-amazed/" target="_blank" rel="noopener">Why Is Hope Important In Life? You Will Be Amazed!</a></span></h3>
<h3 style="text-align: center;"><span style="color: #0000ff;"><a style="color: #0000ff;" href="https://goodshepherdmedia.net/the-freedom-of-forgiveness/" target="_blank" rel="noopener">The Freedom of Forgiveness</a></span></h3>
<h3 style="text-align: center;"><span style="color: #0000ff;"><a style="color: #0000ff;" href="https://goodshepherdmedia.net/why-is-faith-important-in-recovery/" target="_blank" rel="noopener">Why Is Faith Important in Recovery?</a></span></h3>
<p><iframe title="Robert Downey Jr EPIC speech about Sobriety, God, Hope &amp; Forgiveness" width="640" height="360" src="https://www.youtube.com/embed/fhBe8QowV3M?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe></p>
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		<title>Why Is Faith Important in Recovery?</title>
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		<dc:creator><![CDATA[The Truth News]]></dc:creator>
		<pubDate>Thu, 16 Feb 2023 11:52:08 +0000</pubDate>
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					<description><![CDATA[Why Is Faith Important in Recovery? Faith can play a significant role in personal growth. Whether one considers themselves spiritual, religious, or neither, faith remains one of the essential steps in addiction recovery. Why is this so? What Is Faith? Faith is a term interconnected to spirituality and religion, although faith is not just believing [&#8230;]]]></description>
										<content:encoded><![CDATA[<h1 class="entry-title" style="text-align: center;">Why Is Faith Important in Recovery?</h1>
<div class="entry-content">
<p>Faith can play a significant role in personal growth. Whether one considers themselves spiritual, religious, or neither, faith remains one of the essential steps in addiction recovery. Why is this so?</p>
<h2><strong>What Is Faith?</strong></h2>
<p id="Why-Is-Faith-Important-in-Recovery?-">Faith is a term interconnected to spirituality and religion, although faith is not just believing in a Higher Power. One does not have to experience religion for faith to play a role in recovery, either. In more general terms, faith is expressing hope for something greater or better to come. Faith is different from believing because beliefs are rooted in the conscious mind. When intentionally practiced, faith can be powerfully rooted in the subconscious mind, fostering more positive thoughts and attitudes about the recovery process. A positive subconscious mind will facilitate more extraordinary conscious actions towards sobriety.</p>
<h2><strong>Faith Fosters Forgiveness</strong></h2>
<p>Where there is faith, there is forgiveness. Addiction is more than an ongoing battle with a particular substance or an activity. Addiction takes its toll on friendships and family relationships and can negatively affect the relationship that one has with themselves. While recovery begins with acknowledging the problem at hand, mistakes can and still do happen.</p>
<p>With all of this comes the personal need for forgiveness. Some may seek forgiveness from loved ones, and many may seek forgiveness from themselves. Forgiveness involves releasing expectations that were once set about how someone should act or behave, and instead, accepting others for who they are. Forgiveness ties into faith because it is a combination of releasing expectations and working towards something better. Faith teaches how to forgive others and to forgive oneself. Forgiving oneself may be one of the most challenging acts to do in recovery, but it is a necessary part of the process.</p>
<h2><strong>Faith Fosters Confidence<img loading="lazy" decoding="async" class="size-large wp-image-12061 alignright" src="https://goodshepherdmedia.net/wp-content/uploads/2023/02/pablo-heimplatz-EAvS-4KnGrk-unsplash-1080x675-1-1024x640.jpg" alt="" width="640" height="400" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/02/pablo-heimplatz-EAvS-4KnGrk-unsplash-1080x675-1-1024x640.jpg 1024w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/pablo-heimplatz-EAvS-4KnGrk-unsplash-1080x675-1-400x250.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/pablo-heimplatz-EAvS-4KnGrk-unsplash-1080x675-1-768x480.jpg 768w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/pablo-heimplatz-EAvS-4KnGrk-unsplash-1080x675-1.jpg 1080w" sizes="(max-width: 640px) 100vw, 640px" /></strong></h2>
<p>Another reason faith is so crucial in the recovery process is that it builds individuals’ confidence to ask for help. Once an addiction has been acknowledged, it takes dedication and motivation to continue the recovery process. Many may struggle with asking for the next step to take in their journey, especially when asking where to begin in the first place. When one has faith that their situation will get better, they are more likely to accept help and let others help them on their journey. Addiction recovery is not meant to be experienced alone.</p>
<h2><strong>Faith Fosters Support</strong></h2>
<p>When an individual recognizes the need for recovery, life can start to feel like a standstill. But many forget that acknowledging the need for change is one of the most challenging steps in the recovery process. Once it is recognized, the individual seeking help needs encouragement and support from their community to find resources and opportunities for recovery.</p>
<p>It is common for family and friends to identify addiction before an individual identifies with it themselves. The faith that family and friends hold for a specific individual is powerful. It may be just as important and influential as the faith built by the individual struggling with addiction. It is necessary to express faith to anyone experiencing a journey of recovery. It recognizes that their battle will be difficult but reiterates that their battle is not impossible to win. More so, to instill faith in the heart of someone experiencing addiction is to instill empathy and a great love for humanity as a whole.</p>
<h2><strong>How to Gain Faith</strong></h2>
<p>Faith is a necessary part of recovery. However, how does one gain the confidence to have faith in their recovery? One place to start would include community support groups. Support groups give individuals an opportunity to connect with others experiencing the same obstacles in their lives. Experiencing a community support group can help individuals to feel empowered in their recovery process, regardless of where they are in their journey.</p>
<p>Support groups also help normalize mistakes that may happen over time and help others make connections with people who want to better their lives. It says a lot for someone to walk into a support group, let alone stick with it for some time. It is a beautifully difficult, incredibly brave step to surrender one’s struggle to a group of strangers. However, it helps when everyone else wants to be better and wants others to be better, too.</p>
<p>Another way to gain the confidence to have faith in recovery would be to listen to stories from those that consider themselves “recovered.” Some so many people have walked the same shoes, have experienced the same addiction, and are no longer in the place of suffering. Their stories are insightful, encouraging, and uplifting. It helps to hear that recovery is experienced by many people and overcome by many as well. These individuals will tell you about their continuous faith in themselves and their willingness to push forward despite their intensely difficult journeys. Listening to stories of faith will instill faith within.</p>
<h2><strong>Faith Is Crucial in Recovery</strong></h2>
<p>Cambridge Dictionary defines faith as “great trust or confidence in something or someone.” For those that are in recovery and are religious, having faith may look like trusting God for the ability to endure personal healing. For those that are in recovery and are not religious, having faith may be building up personal confidence in oneself to overcome addiction. Regardless, having faith in something or someone empowers individuals to keep moving forward.</p>
<p>Recovery becomes more intentional when faith is involved. Faith helps with the forgiveness of others and oneself and helps build the confidence to ask for help. Seek connections with others that will help to foster faith within. Take time to listen to stories of faith and the long-lasting effects that come with it. Faith just may be the most necessary part of one’s recovery process.</p>
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<p><iframe title="Prayers for Sobriety" width="640" height="360" src="https://www.youtube.com/embed/G4QYur58tg4?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe></p>
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<h2>The Advantages of Prayer for Addiction Recovery</h2>
<p>Many people underestimate the effects of prayer in our lives, but for someone in recovery from a substance abuse problem, praying can come with several added benefits. At Faith in Recovery, we are looking at the power of Christian prayer for recovery to help you through the good times and the bad.</p>
<p>At Faith in Recovery, we understand that reading scripture and prayer can help people recovering from substance abuse heal from the inside out. A person’s spiritual state should never be neglected in sobriety.</p>
<h2>The Benefits of Prayer for Drug Addiction</h2>
<p>A.W. Tozer famously said, “What comes to your mind when you think about God is the most important thing about you.” If you see God as slow to anger and abounding in loving-kindness (Exodus 34:6), then you’re more likely to find comfort in prayer for addiction recovery.</p>
<p>While many people underestimate the effects of prayer in our lives, praying can come with several added benefits for someone recovering from a substance use problem. At our Christian drug rehabilitation center, we look at the power of scripture and Christian prayer in recovery to help you through the good times and the bad.</p>
<h3>Hope</h3>
<p>Recovery from addiction can be a trying time. There may be days when you feel like giving up and caving into your cravings, but one of the benefits of praying in addiction recovery is that it can give you hope. When you are feeling weak or struggling, “Do not grieve, for the joy of the Lord is your strength” (Nehemiah 8:10). Praying can also remind you that you are never alone in your recovery journey and give you hope for a better future.</p>
<h3>Improved Mental Health</h3>
<p>Drugs and alcohol can have a major impact on a person’s mental health. Fortunately, prayer also addresses these issues. Some research suggests that regularly praying can lead to mental health benefits. In some cases, prayer has been found to reduce anger, feelings of aggression, anxiety, and depression. <sup>1,2</sup> Prayer can offer some relief for someone in early recovery who may be experiencing these emotions frequently as they adjust to a new lifestyle.</p>
<h3>Self-Reflection</h3>
<p>Another advantage of prayer for addiction recovery is its promotion of daily self-reflection. We see this often in clients who recently completed one of our faith-based addiction recovery programs and are new to recovery. These individuals are often still trying to figure out how to navigate their sobriety.</p>
<p>Life can be overwhelming, drug triggers can be everywhere, and there are both good and bad days. However, prayer in recovery allows people to properly manage these distractions and get through difficult moments. As it says in 1 Corinthians 10:13, “No temptation has overtaken you except such as is common to man; but God is faithful, who will not allow you to be tempted beyond what you are able, but with the temptation will also make the way of escape, that you may be able to bear it.” This moment of pause can help individuals in recovery better recognize their emotions and responses to distractions, as well as learn how to react better in the future.</p>
<p>&nbsp;</p>
<h3>Routine</h3>
<p>Many people in recovery benefit from having a set routine in place. In fact, this is something we recommend to all patients in our Christian-based recovery programs. A schedule keeps them going when they may otherwise get complacent with their sobriety. It also leaves less room for boredom.</p>
<p>One of the many benefits of praying every day in recovery is that it helps keep a routine. Whether you pray when you first wake up or right before bed, these few minutes of prayer can help you get back into your routine when you may have otherwise started to stay away from the healthy routine you originally created.</p>
<p>&nbsp;</p>
<h3>Physical Health Benefits</h3>
<p>There may also be some physical health benefits of prayer for sobriety. Research has found correlations between positive religious coping, like praying, among hospitalized patients with improvements in physical health.3 For people in recovery whose bodies are still healing from the damaging effects of drugs and alcohol, praying may help them remain patient, hopeful, and consistent through this process.</p>
<p>&nbsp;</p>
<h3>Better Self Control</h3>
<p>One of the most important benefits of prayer for addiction recovery is its association with better self-control.4 Studies have found that people assigned to pray on a daily basis were found to have better self-control over their drinking habits and drink considerably less than the control group.5 This increased sense of self-control can further reduce the risk of relapse.</p>
<p>&nbsp;</p>
<h2>Prayer for the Addicted &amp; Recovery</h2>
<p>While most substance abuse treatment programs address the physical damage of drug or alcohol abuse, the person’s spiritual state may be put on the back burner. At our residential Christian-based rehab, we believe that prayer is an important part of the recovery journey.</p>
<p>Below are some prayers and Bible verses for addiction recovery that may offer you or a loved one some much-needed support.</p>
<p>&nbsp;</p>
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<h3>The Serenity Prayer by Reinhold Niebuhr</h3>
<p>The Serenity Prayer is as follows: “God, grant me the serenity to accept the things I cannot change, courage to change the things I can, and the wisdom to know the difference.” This prayer focuses on releasing your need for control and leaving things in God’s hands. It emphasizes the importance of humility, courage, and wisdom, which are great things to keep in mind during recovery.</td>
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<h3>1 Corinthians 10:13</h3>
<p>What better prayer to use than a bible verse? In 1 Corinthians 10:13, Paul wrote, “No temptation has overtaken you except what is common to mankind. And God is faithful; He will not let you be tempted beyond what you can bear. But when you are tempted, He will also provide a way out so that you can endure it.” This prayer is often linked to addiction recovery because it reminds us that regardless of the temptation we succumb to, God will always provide us with a way out. However, you must decide to recover and stay sober.</td>
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<h3>1 Corinthians 6:12</h3>
<p>Another well-known Bible verse that can be used as a recovery prayer is 1 Corinthians 6:12, which reads, “‘I have the right to do anything,’ you say&#8211;but not everything is beneficial. ‘I have the right to do anything’ &#8212; but I will not be mastered by anything.” Simply put, this prayer emphasizes that just because you can do something doesn’t mean you should. You may have access to drugs and alcohol, but that doesn’t mean substance abuse is beneficial. The verse also warns against allowing something to take hold of you, as addiction does to so many.</td>
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<h3>Jeremiah 17:14</h3>
<p>“Heal me, Lord, and I will be healed; save me, and I will be saved, for You are the one I praise.” This verse can be very helpful for individuals in recovery who are looking for the strength to continue working to get clean. It can be seen as a prayer for addicts. It also complements the 12 steps of recovery.</td>
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<h3>John 14:27</h3>
<p>“Peace is what I leave with you; it is my own peace that I give you. I do not give it as the world does. Do not be worried and upset; do not be afraid.” Anything having to do with addiction can be terrifying, especially if an overdose has occurred. It can also be a scary time for parents, spouses, and siblings who have witnessed a loved one struggle with drug or alcohol abuse. This verse can offer comfort to both.</td>
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<h1 style="text-align: center;">Faith: An Overlooked Tool in Substance Abuse Prevention and Recovery</h1>
<p>There are 20 million Americans afflicted with a substance use disorder (SUD). And tragically, each year, nearly 160,000 die from alcohol or drug-related deaths. However, as we head further into the 30th annual National Recovery Month, one of the most effective tools to prevent and/or recover from addiction is often overlooked—faith. And when it comes to prevention, particularly among youth, faith is a driving force, according to a new report I co-authored with my daughter, Melissa, which was published in the <em>Journal of Religion and Health</em>. The report is the second commissioned by the interdenominational initiative, Faith Counts to examine the socio-economic contribution of religion to America.</p>
<p><img loading="lazy" decoding="async" class="size-full wp-image-12063 alignright" src="https://goodshepherdmedia.net/wp-content/uploads/2023/02/screen-shot-2019-09-15-at-7-24-11-pm-w640.png" alt="" width="640" height="357" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/02/screen-shot-2019-09-15-at-7-24-11-pm-w640.png 640w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/screen-shot-2019-09-15-at-7-24-11-pm-w640-400x223.png 400w" sizes="(max-width: 640px) 100vw, 640px" /></p>
<p>Unfortunately, most Americans will find this surprising. In the latest Gallup survey, only 46% of Americans think that religion can answer today’s problems, but the reality is that religion provides answers for one of today’s biggest problems—addiction. Part of the misperception revealed in the poll is that fewer people are affiliated with religion today, resulting in less experience with faith and its positive impacts.</p>
<p>So, what are the positive impacts of religion on substance abuse/addiction that are outlined in the new study?</p>
<p>Overwhelmingly, research shows that youth who are spiritually active, participate in a faith community, and invest in a prayerful relationship with their God are less likely to use or abuse drugs and alcohol. By contrast, teens who do not consider religious belief important are almost three times more likely to smoke, five times more likely to binge on alcohol, and almost eight times more likely to use marijuana compared with the teens who strongly appreciated the significance of religion in their daily lives. And compared with the teens who attended religious services at least weekly, the teens who never attended services were twice more likely to drink, over twice more likely to smoke, over three times more likely to use marijuana or binge on alcohol, and four times more likely to use illicit drugs.</p>
<p>A host of empirical studies also reveal that faith among adolescents and young adults can act as a powerful deterrent against drug and alcohol abuse, even when controlling for other contributory factors (e.g., depression). Higher degrees of religiosity among youth, including religious attendance, involvement, and reliance on religious beliefs in decision-making, are associated with several benefits, such as limited depression and negative attitudes toward substance abuse. Adolescents who frequently attend religious services, who are involved in faith-based activities, and who place a high value on spirituality exhibit greater resilience when facing the stressors that can lead to the formative use of drugs and alcohol as a coping mechanism.</p>
<p>Studies also show that high school students’ attendance in religious services and their incorporation of prayer into their everyday lives can equip them with vital spiritual and moral guidance that will decrease their inclinations for drugs and alcohol when stressors arise.</p>
<p><img loading="lazy" decoding="async" class="size-full wp-image-12065 alignright" src="https://goodshepherdmedia.net/wp-content/uploads/2023/02/screen-shot-2019-09-15-at-7-39-15-pm-w640.png" alt="" width="640" height="241" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/02/screen-shot-2019-09-15-at-7-39-15-pm-w640.png 640w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/screen-shot-2019-09-15-at-7-39-15-pm-w640-400x151.png 400w" sizes="(max-width: 640px) 100vw, 640px" /></p>
<p>The evidence on the association between religious involvement and/or religiosity and reduced risk of substance use among adolescents is overwhelming. Teens who attend religious services weekly are less likely to smoke, drink, use marijuana or other illicit drugs (e.g., LSD, cocaine, and heroin) than those who attend religious services less frequently. Further, religious practice among teens discourages them from taking highly dangerous drugs. For example, people who attended religious services at least weekly in childhood and adolescence were 33% less likely to use illegal drugs.</p>
<p>Adolescents also benefit from their mothers’ higher levels of religious practice, controlling for factors that also influence the level of drinking (e.g., the adolescents’ peer associations). Higher teenage religiosity is also related to other factors related to a decrease in drug use, such as good family relations, high academic performance in school, having anti-drug attitudes, and socializing with friends who do not take drugs. Moreover, teens themselves tend to cite their peers’ religious and spiritual inclinations as reasons that discourage their peers from drinking and taking drugs.</p>
<p>Our study concludes that the decline in religious affiliation presents a growing <em>national health concern </em>because the growth of disaffiliation is concentrated among Millennials and young adults, who are also the highest percentage of any age group to have a substance abuse disorder. In a sense, the antidote is being rejected by the very people who need it most.<a href="https://westcoastrecoverycenters.com/why-is-faith-important-in-recovery/#:~:text=Faith%20Is%20Crucial%20in%20Recovery&amp;text=Regardless%2C%20having%20faith%20in%20something,confidence%20to%20ask%20for%20help." target="_blank" rel="noopener">source</a> <a href="https://faithinrecovery.com/2020/08/19/benefits-of-prayer-in-recovery/" target="_blank" rel="noopener">source</a> <a href="https://ifstudies.org/blog/faith-an-overlooked-tool-in-substance-abuse-prevention-and-recovery" target="_blank" rel="noopener">source</a></p>
<p>&nbsp;</p>
<h3 style="text-align: center;"><span style="color: #0000ff;"><a style="color: #0000ff;" href="https://goodshepherdmedia.net/the-health-benefits-of-being-sober/" target="_blank" rel="noopener">The Health Benefits of Being Sober</a></span></h3>
<h3 style="text-align: center;"><span style="color: #0000ff;"><a style="color: #0000ff;" href="https://goodshepherdmedia.net/the-importance-of-being-trustworthy/" target="_blank" rel="noopener">The Importance of Being Trustworthy</a></span></h3>
<h3 style="text-align: center;"><span style="color: #0000ff;"><a style="color: #0000ff;" href="https://goodshepherdmedia.net/why-is-hope-important-in-life-you-will-be-amazed/" target="_blank" rel="noopener">Why Is Hope Important In Life? You Will Be Amazed!</a></span></h3>
<h3 style="text-align: center;"><span style="color: #0000ff;"><a style="color: #0000ff;" href="https://goodshepherdmedia.net/the-freedom-of-forgiveness/" target="_blank" rel="noopener">The Freedom of Forgiveness</a></span></h3>
<h3 style="text-align: center;"><span style="color: #0000ff;"><a style="color: #0000ff;" href="https://goodshepherdmedia.net/why-is-faith-important-in-recovery/" target="_blank" rel="noopener">Why Is Faith Important in Recovery?</a></span></h3>
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		<title>What are the first-line medications to treat and prevent a stroke?</title>
		<link>https://goodshepherdmedia.net/what-are-the-first-line-medications-to-treat-and-prevent-a-stroke/</link>
		
		<dc:creator><![CDATA[The Truth News]]></dc:creator>
		<pubDate>Fri, 29 Jul 2022 10:24:38 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Top Stories]]></category>
		<category><![CDATA[Zee Truthful News]]></category>
		<category><![CDATA[🧠Stroke⚕️🏥]]></category>
		<category><![CDATA[medications]]></category>
		<category><![CDATA[medications for stroke]]></category>
		<category><![CDATA[medications to prevent stroke]]></category>
		<category><![CDATA[medications to treat stroke]]></category>
		<category><![CDATA[treat stroke]]></category>
		<guid isPermaLink="false">https://goodshepherdmedia.net/?p=11238</guid>

					<description><![CDATA[What are the first-line medications to treat and prevent a stroke? Medications for stroke work in different ways. Some help prevent stroke, while others can help treat a stroke during an emergency. These medications include tissue plasminogen activators, antiplatelets, and anticoagulants. A stroke occurs when either an artery bursts or a blockage in the arteries [&#8230;]]]></description>
										<content:encoded><![CDATA[<h1 class="css-0">What are the first-line medications to treat and prevent a stroke?</h1>
<p>Medications for stroke work in different ways. Some help prevent stroke, while others can help treat a stroke during an emergency. These medications include tissue plasminogen activators, antiplatelets, and anticoagulants.</p>
<div class="css-1u22pos">
<p class="responsive">A stroke occurs when either an artery bursts or a blockage in the arteries prevents oxygen-rich blood from reaching the brain.</p>
<p class="responsive">When this occurs, brain cells in part of the brain can start to die off within minutes<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span>. The resulting damage can lead to disability and potential fatality.</p>
<p class="responsive">Medications for stroke aim to:</p>
<ul class="responsive">
<li>help break up blood clots</li>
<li>reduce blood pressure and cholesterol levels</li>
<li>help prevent blood clots</li>
</ul>
<p class="responsive">Once a person has had a stroke, they have about a 25%<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span> chance of having another within 5 years. This makes taking preventive steps, such as taking medications and lifestyle changes, important.</p>
<p class="responsive">This article will provide information on the available medications to help prevent and treat a stroke.</p>
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<div><a class="chartbeat-section" name="overview-table"></a>Overview table</div>
<p class="responsive">The following table provides an overview of the medications available to treat a stroke:</p>
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<th scope="col">Type</th>
<th scope="col">Examples</th>
<th scope="col">Use</th>
<th scope="col">Potential side effects</th>
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<th scope="row">tissue plasminogen activator (tPA)</th>
<td>tPA injection, or Alteplase</td>
<td>breaks up a clot that is causing the stroke</td>
<td>• bleeding<br />
• bruising<br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/167533">pulmonary edema</a><br />
• arterial embolism<br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/153704">deep vein thrombosis</a><br />
• swelling of the lips and tongue<br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/317080">intracranial hemorrhage</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/326959">shock</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/269511">nausea and vomiting</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/seizure">seizure</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/7624">stroke</a><br />
• thromboembolism, a type of blood clot<br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/305782">sepsis</a></td>
</tr>
<tr>
<th scope="row">antiplatelets</th>
<td>• aspirin<br />
• dipyridamole<br />
• clopidogrel<br />
• ticagrelor</td>
<td>reduce the ability of platelets in the blood to clump together</td>
<td>• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/headaches">headaches</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/318275">heart palpitations</a><br />
• bleeding risks</td>
</tr>
<tr>
<th scope="row">anticoagulants</th>
<td>• warfarin<br />
• rivaroxaban<br />
• dabigatran<br />
• apixaban<br />
• edoxaban</td>
<td>help keep the blood from clotting</td>
<td>• excessive bleeding<br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/150322">constipation</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/158634">diarrhea</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/325251">dizziness</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/163484">indigestion</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/317999">rashes</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/311473">itchy skin</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/165749">jaundice</a><br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/70956">hair loss</a><br />
• nausea and vomiting</td>
</tr>
<tr>
<th scope="row">statins</th>
<td>• simvastatin<br />
• atorvastatin<br />
• lovastatin<br />
• fluvastatin<br />
• pravastatin<br />
• pitavastatin<br />
• rosuvastatin</td>
<td>help lower cholesterol</td>
<td>• nausea<br />
• dizziness<br />
• feeling weak<br />
• constipation<br />
• diarrhea<br />
• <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/7622">gas</a><br />
• sleep problems<br />
• headache</td>
</tr>
<tr>
<th scope="row">blood pressure medication</th>
<td>calcium channel blockers, including:<br />
• bepridil<br />
• diltiazem hydrochloride<br />
• nisoldipine<br />
• verapamil hydrochloride<br />
• felodipine<br />
• isradipine<br />
• nicardipine<br />
• amlodipine besylate<br />
• nifedipineangiotensin-converting enzyme (ACE) inhibitors, including:<br />
• trandolapril<br />
• captopril<br />
• enalapril maleate<br />
• ramipril<br />
• fosinopril sodium<br />
• lisinopril<br />
• moexipril<br />
• perindopril<br />
• quinapril hydrochloride<br />
• benazepril hydrochloride</p>
<p>other blood pressure medications include:<br />
• diuretics<br />
• beta-blockers<br />
• angiotensin II receptor blockers<br />
• vasodilators<br />
• alpha blockers</td>
<td>help lower blood pressure</td>
<td>• erection issues<br />
• headaches<br />
• tiredness or fatigue<br />
• nervousness</td>
</tr>
</tbody>
</table>
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<div><a class="chartbeat-section" name="t-pa-injection"></a>Tissue plasminogen activator (tPA)</div>
<p class="responsive">To treat a stroke, a doctor may administer the tPA, called Alteplase, which can help break up a blood clot.</p>
<p class="responsive">A doctor will likely administer tPA if a person reaches a hospital within the first <a class="content-link css-1pg8eb5" href="https://www.cdc.gov/stroke/treatments.htm" target="_blank" rel="noopener noreferrer">3 hours<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span></a> of a stroke.</p>
<p class="responsive">The medication can help improve a person’s chance of recovering from a stroke. However, many people do not reach the emergency room in time, meaning they might not be able to benefit from the medication.</p>
<p class="responsive">Doctors administer the medication directly into the veins so that it reaches the clot quickly.</p>
<h3 class="responsive">Side effects</h3>
<p class="responsive">Side effects can occur in <a class="content-link css-1pg8eb5" href="https://www.ncbi.nlm.nih.gov/books/NBK507917/" target="_blank" rel="noopener noreferrer">1–10%<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span></a> of people, the most common being bleeding. Other side effects include:</p>
<ul class="responsive">
<li>bleeding</li>
<li>bruising</li>
<li>pulmonary edema, a buildup of fluid in the lungs</li>
<li>arterial embolism, a type of blood clot</li>
<li>deep vein thrombosis</li>
<li>swelling of the lips and tongue</li>
<li>intracranial hemorrhage, a bleed in the skull or brain</li>
<li>shock</li>
<li>nausea</li>
<li>vomiting</li>
<li>seizure</li>
<li>stroke</li>
<li>thromboembolism, a type of blood clot</li>
<li>sepsis</li>
</ul>
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<div><a class="chartbeat-section" name="antiplatelet-drugs"></a>Antiplatelet drugs</div>
<p class="responsive">Antiplatelet medications help prevent platelets in the blood from sticking together, which assists in preventing blood clotting.</p>
<p class="responsive">A doctor may prescribe this type of medication to help prevent ischemic strokes or transient ischemic attacks. Ischemic strokes account for 87%<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span> of all cases of stroke and involve blood clots that cut off the blood supply to the brain.</p>
<p class="responsive">A transient ischemic attack occurs when blood temporarily does not reach the brain, but the condition resolves quickly with no damage. However, they may be an early warning sign of a stroke.</p>
<p class="responsive">Some examples of antiplatelet drugs include<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span>:</p>
<ul class="responsive">
<li>aspirin</li>
<li>aspirin-dipyridamole</li>
<li>clopidogrel</li>
<li>ticagrelor</li>
</ul>
<p class="responsive">According to a 2019 study<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span>, antiplatelet medication may have several limitations, including a lack of studies examining their long-term use, using them for acute stroke, and adherence to treatment among individuals.</p>
<p class="responsive">A person’s doctor will assess a person’s needs and recommend dosing for the medication.</p>
<h3 class="responsive">Side effects</h3>
<p class="responsive">Headaches and heart palpitations are common side effects. People may also have an elevated risk<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span> of bleeding events<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span>, such as intracranial hemorrhage and gastrointestinal bleeding.</p>
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<div><strong>Anticoagulants</strong></div>
<p class="responsive">Anticoagulants prevent the blood from clotting easily. A doctor may prescribe them to help prevent ischemic stroke.</p>
<p class="responsive">Common anticoagulants include<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span>:</p>
<ul class="responsive">
<li>warfarin</li>
<li>rivaroxaban</li>
<li>dabigatran</li>
<li>apixaban</li>
<li>edoxaban</li>
</ul>
<p class="responsive">However, experts do not recommend these for everyone. People with bleeding conditions should avoid this type of medication. Those with liver or kidney issues may also want to avoid using these medications.</p>
<h3 class="responsive">Side effects</h3>
<p class="responsive">The United Kingdom’s National Health Service (NHS) states that anticoagulants can lead to excessive bleeding. Signs of excessive bleeding include:</p>
<ul class="responsive">
<li>blood in the urine</li>
<li>blood in the stool</li>
<li>severe bruising</li>
<li>vomiting or coughing up blood</li>
<li>prolonged nosebleeds, that last longer than 10 minutes</li>
<li>chest pain</li>
<li>difficulty breathing</li>
<li>back pain</li>
<li>increased bleeding during periods</li>
</ul>
<p class="responsive">Other side effects include:</p>
<ul class="responsive">
<li>constipation</li>
<li>diarrhea</li>
<li>dizziness</li>
<li>indigestion</li>
<li>rashes</li>
<li>itchy skin</li>
<li>jaundice</li>
<li>hair loss</li>
<li>nausea and vomiting</li>
</ul>
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<div>Statins</div>
<p class="responsive">The American Heart Association (AHA)<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span> notes that statins are a type of medication to help lower cholesterol. People with high cholesterol use these medications to help prevent certain liver enzymes from creating more cholesterol, lowering the chances of a blockage.</p>
<p class="responsive">Several statins have approval for use in the United States, which include:</p>
<ul class="responsive">
<li>simvastatin (Zocor)</li>
<li>atorvastatin (Lipitor)</li>
<li>lovastatin (Altoprev)</li>
<li>fluvastatin (Lescol)</li>
<li>pravastatin (Pravachol)</li>
<li>pitavastatin (Livalo)</li>
<li>rosuvastatin (Crestor)</li>
</ul>
<h3 class="responsive">Side effects</h3>
<p class="responsive">Statins can cause side effects, including:</p>
<ul class="responsive">
<li>nausea</li>
<li>dizziness</li>
<li>feeling weak</li>
<li>constipation</li>
<li>diarrhea</li>
<li>gas</li>
<li>sleep problems</li>
<li>headache</li>
<li>muscle weakness</li>
</ul>
<p class="responsive">Uncommon side effects include:</p>
<ul class="responsive">
<li>being sick</li>
<li>hair loss</li>
<li>hepatitis, or inflammation of the liver</li>
<li>pancreatitis, or inflammation of the pancreas</li>
</ul>
<p class="responsive">In rare cases, statins can cause muscle weakness, tendon problems, and peripheral neuropathy. This is a loss of sensation or tingling in the feet and hands.</p>
<p class="responsive">According to a 2019 study<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span>, around 50% of people who start statins discontinue them due to the potential for side effects. However, the study authors also noted that the benefits, including stroke prevention, far outweigh the potential risks.</p>
<div>Blood pressure medication</div>
<p class="responsive">Blood pressure medication helps lower high blood pressure. High blood pressure typically shows no symptoms<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span> but can lead to cardiovascular events, including heart attack and stroke.</p>
<p class="responsive">Medications for blood pressure can help prevent plaque from breaking free of the artery wall and causing a stroke.</p>
<p class="responsive">According to a 2019 study<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span>, calcium channel blockers and ACE inhibitors can help lower blood pressure and help prevent stroke.</p>
<p class="responsive">Calcium channel blockers help prevent<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span> the absorption of calcium in the heart. Calcium helps the heart beat with more force, which can increase blood pressure.</p>
<p class="responsive">Examples of calcium channel blockers include:</p>
<ul class="responsive">
<li>bepridil (Vasocor)</li>
<li>diltiazem hydrochloride (Cardizem CD, Cardizem SR, Dilacor XR, and Tiazac)</li>
<li>nisoldipine (Sular)</li>
<li>verapamil hydrochloride (Calan SR, Covera HS, Isoptin SR, and Verelan)</li>
<li>felodipine (Plendil)</li>
<li>isradipine (DynaCirc and DynaCirc CR)</li>
<li>nicardipine (Cardene SR)</li>
<li>amlodipine besylate (Norvasc and Lotrel)</li>
<li>nifedipine (Adalat CC and Procardia XL)</li>
</ul>
<p class="responsive">ACE inhibitors help block a chemical known as angiotensin, a chemical responsible for narrowing the arteries. By blocking angiotensin, the medication helps the blood flow more freely through the arteries.</p>
<p class="responsive">Examples of ACE inhibitors include:</p>
<ul class="responsive">
<li>trandolapril (Mavik)</li>
<li>captopril (Capoten)</li>
<li>enalapril maleate (Vasotec)</li>
<li>ramipril (Altace)</li>
<li>fosinopril sodium (Monopril)</li>
<li>lisinopril (Prinivel or Zestril)</li>
<li>moexipril (Univasc)</li>
<li>perindopril (Aceon)</li>
<li>quinapril hydrochloride (Accupril)</li>
<li>benazepril hydrochloride (Lotensin)</li>
<li>diuretics</li>
</ul>
<h3 class="responsive">Side effects</h3>
<p class="responsive">These medications can cause different side effects, including difficulty achieving and maintaining erections, fatigue, nausea, headaches, and nervousness.</p>
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<div>Which medications help prevent stroke?</div>
<p class="responsive">Several different types of medication can help prevent stroke. They include:</p>
<ul class="responsive">
<li>antiplatelets</li>
<li>anticoagulants</li>
<li>statins</li>
<li>blood pressure medications, such as calcium channel blockers and ACE inhibitors</li>
<li>diuretics</li>
</ul>
<p class="responsive">A person should work with a doctor to determine the best medication to help them prevent having a stroke in the future.</p>
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<div>Which medications will a person need to take after a stroke has happened?</div>
<p class="responsive">If a person recognizes the signs of stroke in themselves or someone they are with, they should call 911.</p>
<p class="responsive">Paramedics can diagnose and start treating the stroke immediately. If a person seeks medical attention within 3 hours<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span> of a stroke first appearing, doctors in the emergency room will likely administer an injection of tPA.</p>
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<div>How to take the medication</div>
<p class="responsive">A person should speak with a doctor about how to take each medication. They should take all medication as a healthcare professional prescribes and consult a doctor before stopping any medication.</p>
<p class="responsive">Some medications may require food, while others only need a drink to help swallow the pills. A person should read all labels carefully before taking their medications.</p>
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<div>Paying for stroke medication</div>
<p class="responsive">People who need help paying for their medications could use different financial aid options.</p>
<p class="responsive">There are several programs exist that can help a person in need of financial assistance for medication. They can access a list of organizations to apply for help here<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span>.</p>
<p class="responsive">Often, they will need basic information, including:</p>
<ul class="responsive">
<li>names and dosage of current medications</li>
<li>monthly or yearly income</li>
<li>insurance provider, if any</li>
<li>state of residency</li>
</ul>
<p class="responsive">Another potential source of help could come from the doctor or pharmacy. They may be able to provide coupons to help reduce the cost or recommend cheaper generic brands as substitutes.</p>
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<div>Summary</div>
<p class="responsive">Medications for stroke aim to either prevent or help treat one if it occurs. Most medications aim to reduce the recurrence of stroke either by making it easier for blood to flow through the body or reducing cholesterol levels in the blood.</p>
<p class="responsive">A person should follow all dosing and other instructions that the doctor gives them. They should also not stop taking medications without consulting a doctor first. If an individual experiences side effects, they should let the doctor know. <a href="https://www.medicalnewstoday.com/articles/what-is-the-best-medication-for-stroke#summary" target="_blank" rel="noopener">source</a></p>
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		<title>New drug could flip the script for stroke treatment, but small Canadian biotech needs funding boost</title>
		<link>https://goodshepherdmedia.net/new-drug-could-flip-the-script-for-stroke-treatment-but-small-canadian-biotech-needs-funding-boost/</link>
		
		<dc:creator><![CDATA[The Truth News]]></dc:creator>
		<pubDate>Fri, 29 Jul 2022 01:27:56 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Zee Truthful News]]></category>
		<category><![CDATA[🧠Stroke⚕️🏥]]></category>
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					<description><![CDATA[New drug could flip the script for stroke treatment, but small Canadian biotech needs funding boost Researchers used a new peptide drug in an animal model of severe ischemic stroke and found that it improved motor function, sensory function, spatial learning and memory. (iStock / Getty Images Plus) What Does It Take to Cure Cancer? [&#8230;]]]></description>
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<h1 class="element-title hero mb-0" style="text-align: center;">New drug could flip the script for stroke treatment, but small Canadian biotech needs funding boost</h1>
<blockquote><p><em>Researchers used a new peptide drug in an animal model of severe ischemic stroke and found that it improved motor function, sensory function, spatial learning and memory. (iStock / Getty Images Plus)</em></p></blockquote>
<h3 id="gam-title">What Does It Take to Cure Cancer? Plant Roots of Scientific Discovery and Grow Them into an Ecosystem of Collaboration and Innovation.</h3>
<p>Once a stroke happens, the damage can&#8217;t be repaired by any drug on the market. But scientists think they have found an option that could protect and repair the damage that occurs with a stroke up to a week after onset—but limited resources may block its path to clinic. Providing the right conditions for science to thrive is crucial to uncovering a cure for cancer. Discover ways to cultivate an environment for growth to ultimately make an impact for patients.</p>
<p>There’s only one drug on the market for stroke treatment: <span style="color: #0000ff;"><strong>Activase</strong></span>, sold by Roche&#8217;s Genentech, has to be <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840541/#:~:text=Intravenous%20administration%20of%20alteplase%20is,patients%20with%20acute%20ischemic%20stroke." target="_blank" rel="noopener">administered</a> within 4.5 hours of stroke onset. Most investigational stroke therapies currently under investigation also must be given within one to two days of the condition’s onset.</p>
<p>Researchers now believe they have identified a peptide that could change the script entirely for stroke treatment.</p>
<p>Scientists at the University of Cincinnati and Case Western Reserve University in Cleveland have found that the drug, dubbed NVG-291-R, supports nervous system repair and significant functional recovery in an animal model of severe ischemic stroke, as published in <a href="https://dx.doi.org/10.1016/j.celrep.2022.111137" target="_blank" rel="noopener">Cell Reports</a>.</p>
<p>NVG-291-R reduced neuronal death and showed neuroreparative effects in animal models. The drug repaired damage by forming new neuronal connections and boosting migration of new neurons to the damaged site.</p>
<p>The researchers used NVG-291-R to block signaling pathways known as chondroitin sulfate proteoglycans, resulting in significant behavioral recovery including improved motor function, sensory function, spatial learning and memory. Researchers also found the drug to be effective even when administered as late as seven days after stroke onset.</p>
<p>NervGen Pharma, a clinical-stage biotech based in Canada, currently holds the rights to NVG-291-R and is planning trials in different neuronal damage diseases. Though the aforementioned research assessed the drug’s effect in neurorepair after stroke, NervGen is first launching clinical trials in patients with spinal cord injury, Alzheimer’s disease and multiple sclerosis, starting in 2022 and 2023.</p>
<p>When asked about the absence of stroke patients in its upcoming trial plans, the biotech cited limited resources. NervGen’s initial focus is based on the weight of scientific evidence to support those indications, the potential for positive impact on patients, feasibility of development, investor sentiment and commercial potential.</p>
<p>“Given this compelling new preclinical data in stroke, we believe there is a solid opportunity to secure non-dilutive funding to advance the program in the clinic through a partnership, either with industry or government,” NervGen said.</p>
<p>By <a href="https://www.fiercebiotech.com/person/gabrielle-masson-0" rel="bookmark"><span class="font-weight-bold">Gabrielle Masson</span></a></p>
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<div><a href="https://www.fiercebiotech.com/research/flipping-script-stroke-treatment-new-drug-may-repair-neurodamage-week-later" target="_blank" rel="noopener">source</a></div>
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<div>Med info from their site</div>
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<h3><b>Indications</b></h3>
<p>Activase<sup>®</sup> (alteplase) is indicated for the treatment of acute ischemic stroke. Exclude intracranial hemorrhage as the primary cause of stroke signs and symptoms prior to initiation of treatment. Initiate treatment as soon as possible but within 3 hours after symptom onset.</p>
<p>Activase is indicated for use in acute myocardial infarction (AMI) for the reduction of mortality and reduction of the incidence of heart failure.</p>
<p><u>Limitation of Use:</u> The risk of stroke may outweigh the benefit produced by thrombolytic therapy in patients whose AMI puts them at low risk for death or heart failure.</p>
<p>Activase is indicated for the lysis of acute massive pulmonary embolism (PE), defined as:</p>
<ul>
<li>Acute pulmonary emboli obstructing blood flow to a lobe or multiple lung segments.</li>
<li>Acute pulmonary emboli accompanied by unstable hemodynamics, e.g., failure to maintain blood pressure without supportive measures.</li>
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<h3><b>Important Safety Information</b></h3>
<h4><b>Contraindications</b></h4>
<p>Do not administer Activase to treat acute ischemic stroke in the following situations in which the risk of bleeding is greater than the potential benefit: current intracranial hemorrhage (ICH); subarachnoid hemorrhage; active internal bleeding; recent (within 3 months) intracranial or intraspinal surgery or serious head trauma; presence of intracranial conditions that may increase the risk of bleeding (e.g., some neoplasms, arteriovenous malformations, or aneurysms); bleeding diathesis; and current severe uncontrolled hypertension.</p>
<p>Do not administer Activase to treat acute myocardial infarction or pulmonary embolism in the following situations in which the risk of bleeding is greater than the potential benefit: active internal bleeding; history of recent stroke; recent (within 3 months) intracranial or intraspinal surgery or serious head trauma; presence of intracranial conditions that may increase the risk of bleeding; bleeding diathesis; and current severe uncontrolled hypertension.</p>
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<h4><b>Warnings and Precautions</b></h4>
<h5><i><b>Bleeding</b></i></h5>
<p>Activase can cause significant, sometimes fatal internal or external bleeding, especially at arterial and venous puncture sites. Avoid intramuscular injections and trauma to the patient. Perform venipunctures carefully and only as required. Fatal cases of hemorrhage associated with traumatic intubation in patients administered Activase have been reported. Aspirin and heparin have been administered concomitantly with and following infusion with Activase in the management of acute myocardial infarction and pulmonary embolism. The concomitant administration of heparin and aspirin with and following infusions of Activase for the treatment of acute ischemic stroke during the first 24 hours after symptom onset has not been investigated. Because heparin, aspirin, or Activase may cause bleeding complications, carefully monitor for bleeding, especially at arterial puncture sites. Hemorrhage can occur 1 or more days after administration of Activase, while patients are still receiving anticoagulant therapy. If serious bleeding occurs, terminate the Activase infusion, and treat appropriately.</p>
<p>In the following conditions, the risks of bleeding with Activase are increased and should be weighed against the anticipated benefits: recent major surgery or procedure; cerebrovascular disease; recent intracranial hemorrhage; recent gastrointestinal or genitourinary bleeding; recent trauma; hypertension; acute pericarditis; subacute bacterial endocarditis; hemostatic defects including those secondary to severe hepatic or renal disease; significant hepatic dysfunction; pregnancy; diabetic hemorrhagic retinopathy or other hemorrhagic ophthalmic conditions; septic thrombophlebitis or occluded AV cannula at seriously infected site; advanced age; and patients currently receiving oral anticoagulants, or any other condition in which bleeding constitutes a significant hazard or would be particularly difficult to manage because of its location.</p>
<h5><i><b>Hypersensitivity</b></i></h5>
<p>Hypersensitivity, including urticarial / anaphylactic reactions, have been reported after administration of Activase. Rare fatal outcome for hypersensitivity was reported. Angioedema has been observed during and up to 2 hours after Activase infusion in patients treated for acute ischemic stroke and acute myocardial infarction. In many cases, patients received concomitant angiotensin-converting enzyme inhibitors. Monitor patients treated with Activase during and for several hours after infusion for hypersensitivity. If signs of hypersensitivity occur, e.g. anaphylactoid reaction or angioedema develops, discontinue the Activase infusion and promptly institute appropriate therapy (e.g., antihistamines, intravenous corticosteroids, epinephrine).</p>
<h5><i><b>Thromboembolism</b></i></h5>
<p>The use of thrombolytics can increase the risk of thrombo-embolic events in patients with high likelihood of left heart thrombus, such as patients with mitral stenosis or atrial fibrillation. Activase has not been shown to treat adequately underlying deep vein thrombosis in patients with PE. Consider the possible risk of re-embolization due to the lysis of underlying deep venous thrombi in this setting.</p>
<h5><i><b>Cholesterol Embolization</b></i></h5>
<p>Cholesterol embolism, sometimes fatal, has been reported rarely in patients treated with thrombolytic agents; the true incidence is unknown. It is associated with invasive vascular procedures (e.g., cardiac catheterization, angiography, vascular surgery) and/or anticoagulant therapy.</p>
<h5><i><b>Coagulation Tests May be Unreliable during Activase Therapy</b></i></h5>
<p>Coagulation tests and/or measures of fibrinolytic activity may be unreliable during Activase therapy unless specific precautions are taken to prevent in vitro artifacts. When present in blood at pharmacologic concentrations, Activase remains active under <i>in vitro</i> conditions, which can result in degradation of fibrinogen in blood samples removed for analysis.</p>
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<h4><b>Adverse Reactions</b></h4>
<p>The most frequent adverse reaction associated with Activase therapy is bleeding.</p>
<p><b>Please see <a href="https://www.gene.com/download/pdf/activase_prescribing.pdf" target="_blank" rel="noopener" data-analytics="{\&quot;component\&quot;:\&quot;safetysnippet\&quot;,\&quot;destinationTitle\&quot;:\&quot;full Prescribing Information\&quot;,\&quot;location\&quot;:\&quot;safetybar\&quot;,\&quot;destinationURL\&quot;:\&quot;https://www.gene.com/download/pdf/activase_prescribing.pdf\&quot;,\&quot;type\&quot;:\&quot;external\&quot;}" data-adobe-analytics-id="lnk-72eacc6c4e" data-adobe-analytics-cmp="{&quot;lnk-72eacc6c4e&quot;:{&quot;destinationTitle&quot;:&quot;full Prescribing Information&quot;,&quot;name&quot;:&quot;link&quot;,&quot;location&quot;:&quot;safetybar&quot;,&quot;destinationURL&quot;:&quot;https://www.gene.com/download/pdf/activase_prescribing.pdf&quot;,&quot;type&quot;:&quot;external&quot;,&quot;key&quot;:&quot;lnk&quot;}}">full Prescribing Information</a> for additional Important Safety Information.</b></p>
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<h3><span style="color: #ff00ff;">find out more directly from the company medication site</span> <span style="color: #0000ff;"><a style="color: #0000ff;" href="https://www.activase.com/" target="_blank" rel="noopener">www.activase.com</a></span></h3>
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		<title>Gabapentin &#038; Stroke recovery: How an existing drug may help the brain repair itself</title>
		<link>https://goodshepherdmedia.net/gabapentin-stroke-recovery-how-an-existing-drug-may-help-the-brain-repair-itself/</link>
		
		<dc:creator><![CDATA[The Truth News]]></dc:creator>
		<pubDate>Fri, 17 Jun 2022 10:11:33 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[New Medicine]]></category>
		<category><![CDATA[Top Stories]]></category>
		<category><![CDATA[Zee Truthful News]]></category>
		<category><![CDATA[🧠Stroke⚕️🏥]]></category>
		<category><![CDATA[Gabapentin]]></category>
		<category><![CDATA[Gabapentin & Stroke recovery]]></category>
		<category><![CDATA[help the brain repair itself]]></category>
		<category><![CDATA[Stroke recovery]]></category>
		<guid isPermaLink="false">https://goodshepherdmedia.net/?p=11229</guid>

					<description><![CDATA[Gabapentin &#38; Stroke recovery: How an existing drug may help the brain repair itself after stroke New research in mice shows how doctors may be able to use an anticonvulsive drug to help the brain heal The brain can often find new ways to route signals around damaged areas to restore lost function. A new [&#8230;]]]></description>
										<content:encoded><![CDATA[<h1 style="text-align: center;">Gabapentin &amp; Stroke recovery: How an existing drug may help the brain repair itself after stroke</h1>
<p>New research in mice shows how doctors may be able to use an anticonvulsive drug to help the brain heal</p>
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<ul>
<li><strong>The brain can often find new ways to route signals around damaged areas to restore lost function.</strong></li>
<li><strong>A new study in mice finds that administering a common drug soon after a neurological event can help the brain successfully rewire itself.</strong></li>
<li><strong>If further research validates the study’s conclusions, physicians may have a new tool for preventing permanent stroke damage.</strong></li>
</ul>
<p><a class="content-link css-1pg8eb5" href="https://medicine.osu.edu/find-faculty/non-clinical/neuroscience/andrea-tedeschi-phd" target="_blank" rel="noopener noreferrer">Dr. Andrea Tedeschi</a>, assistant professor in the Department of Neuroscience at Ohio State University Medical Center, explained to <em>Medical News Today</em> why the concept of “brain plasticity” is so important when it comes to understanding brain health:</p>
<blockquote class="css-34gtoi"><p>“‘Brain plasticity’ refers to the innate, or intrinsic, ability to compensate for a lack of functioning areas by, in principle, rewiring spare areas of the nervous system. And it’s something that is really amazing if you think about it because it allows us to repair the nervous system under certain conditions.”</p></blockquote>
<p>Dr. Tedeschi is the corresponding author of a new study in mice that investigates the use of an existing drug to help the brain repair itself after an <strong><a class="content-link css-1pg8eb5" href="https://www.stroke.org/en/about-stroke/types-of-stroke/ischemic-stroke-clots" target="_blank" rel="noopener noreferrer">ischemic stroke<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span></a>.</strong></p>
<p><strong>The study found that administering <a class="content-link css-1pg8eb5" href="https://www.medicalnewstoday.com/articles/323681">gabapentin</a>, an anticonvulsive medication, soon after a stroke helps the brain more effectively work around damaged areas.</strong></p>
<p>Dr. Tedeschi explained: “I think that the way that the drug is [commonly] being prescribed, it’s to deal with the consequences of […] maladaptive changes [that] are now intrinsically wired into the system. So prescribing the drug if [the patients] have some sort of pain or [problematic] excitability of a certain part of the brain […] it’s not going to wipe [it] out.”</p>
<p>By contrast, “[t]he way we intend to use it,” Dr. Tedeschi said, “it’s more or less as a prophylactic type of drug.”</p>
<p>“Administering this class of drugs in an earlier phase, when the system has not yet committed to a maladaptive route, then I think it’s really increasing the chances of something that we call an adaptive response.”</p>
<p>The study appears in <em><a class="content-link css-1pg8eb5" href="https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awac103/6589844?redirectedFrom=fulltext" target="_blank" rel="noopener noreferrer">BRAIN</a></em>.</p>
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<div><a class="chartbeat-section" name="Suppressing-excitability"></a>Suppressing excitability</div>
<p>Gabapentin blocks two proteins, <a class="content-link css-1pg8eb5" href="https://www.sciencedirect.com/science/article/pii/S0005273612004105" target="_blank" rel="noopener noreferrer">alpha-2 delta-1 and alpha-2 delta-2</a>. Unchecked, these two proteins normally increase after an event such as a stroke or brain injury, inhibiting the brain’s ability to re-route lost function.</p>
<p>According to previous research by the same team, gabapentin blockade of alpha-2 delta-1 and alpha-2 delta-2 can prevent their normal inhibitory function, effectively lifting the brakes and enabling nerves to grow and regenerate lost function.</p>
<p>The brain “needs these subunits to be there,” said Dr. Tedeschi, but after a stroke, “they’re setting up the stage to create more excitability across the large area of the neural network and this contributes to the establishment of detrimental conditions.”</p>
<p>“Most of the time,” he said, “what we see is that under conditions where there is some form of plasticity, excitability of networks tends to be suppressed.”</p>
<p><strong>When a neuron is hyperexcitable, it responds to a lower-than-normal stimulus threshold.</strong></p>
<p>Dr. Tedeschi provided an example: “If you put your hands on a hard surface, you’re not supposed to feel pain because you feel like there is a hard surface under your hand. If somehow the signal now is miswired and there is hyperexcitability of the group of neurons that are controlling this mechanical sensation, this information is perceived as a painful stimulus.”</p>
<p>“When there is out-of-control neuronal excitability, then these neurons will respond to a very light, very low threshold input and that can cause muscle contraction even when you don’t want it,” said Dr. Tedeschi.</p>
<p>Spontaneous seizures, pain, and muscle spasms are causally linked to hyperexcitability.</p>
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<div><a class="chartbeat-section" name="Sensory-motor-strokes-in-mouse-models"></a>Sensory-motor strokes in mouse models</div>
<p>The researchers induced ischemal stroke changes in the sensory-motor cortex of male and female mice using a <a class="content-link css-1pg8eb5" href="https://pubmed.ncbi.nlm.nih.gov/23770844/" target="_blank" rel="noopener noreferrer">photothrombotic stroke technique<span class="css-xi2i42 icon-hl-trusted-source-after"><span class="sro">Trusted Source</span></span></a>.</p>
<p><strong>For the mice in the 6-week study who received daily gabapentin, the researches saw a significant recovery of motor control by the end of the study period.</strong></p>
<p>Encouragingly, 2 weeks after treatment with gabapentin ceased, the mice retained that degree of improvement. The untreated mice did not recover motor control to the same extent.</p>
<p>As to whether the recovery of this degree of motor control was the extent of improvement mice may experience after gabapentin, Dr. Tedeschi noted with optimism:</p>
<blockquote class="css-34gtoi"><p>“Yeah, certainly there’s going to be more beneficial effect than what we discover. And this is actually a work in progress. We are trying to dig deeper, and on a daily basis, we are actually discovering new things. This is something that unfortunately, I’m not allowed to discuss, but certainly, there are going to be follow-up studies. Pretty much like every week, we learn new things about the action of these drugs.”</p></blockquote>
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<div><a class="chartbeat-section" name="Much-more-to-investigate"></a>Much more to investigate</div>
<p>Not all of gabapentin’s effects are positive, Dr. Tedeschi cautioned, meaning that there will likely be situations in which gabapentin would not be indicated.</p>
<p><a class="content-link css-1pg8eb5" href="https://weillcornell.org/michaelodell" target="_blank" rel="noopener noreferrer">Dr. Michael W. O’Dell</a>, professor of clinical rehabilitation medicine at Weill Cornell Medicine in New York City, who was not involved in the study, told <em>MNT</em>: “There are always limitations in translating basic science, animal studies to humans, but in so much as this is a well-conducted study it does provide additional insights into the potential of pharmacological enhancement of brain plasticity in humans following stroke.”</p>
<p><strong>“It should be pointed out, however, that in practice, in well-designed, larger clinical trials, there has not been a great deal of success in this area,” he noted.</strong></p>
<p>“From a clinical standpoint,” Dr. O’Dell, added, “the fact that gabapentin is a widely available, inexpensive, and relative safe drug is an encouraging aspect of this study should the finding translate to any degree to a human population.”</p>
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<p>By <a class="css-1dkklb9" href="https://www.medicalnewstoday.com/authors/robby-berman">Robby Berman</a> <a href="https://www.medicalnewstoday.com/articles/stroke-recovery-how-an-existing-drug-may-help-the-brain-repair-itself" target="_blank" rel="noopener">source</a></p>
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<h1 class="entry-title" style="text-align: center;">Anticonvulsant Drug May Boost Functional Recovery after a Stroke</h1>
<p style="text-align: center;"><img loading="lazy" decoding="async" class=" wp-image-11232 alignright" src="https://goodshepherdmedia.net/wp-content/uploads/2023/02/stroke-1-1024x577.jpg" alt="" width="878" height="495" srcset="https://goodshepherdmedia.net/wp-content/uploads/2023/02/stroke-1-1024x577.jpg 1024w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/stroke-1-400x225.jpg 400w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/stroke-1-768x433.jpg 768w, https://goodshepherdmedia.net/wp-content/uploads/2023/02/stroke-1.jpg 1114w" sizes="(max-width: 878px) 100vw, 878px" /></p>
<p style="text-align: center;">Scientists at the Ohio State University report that gabapentin, currently prescribed to control seizures and reduce nerve pain, may enhance recovery of movement after a stroke by helping neurons on the undamaged side of the brain take up the signaling work of lost cells.</p>
<p>Their study (“Harnessing cortical plasticity via gabapentinoid administration promotes recovery after stroke”), carried out in mice and published in <em>Brain</em>, mimicked ischemic stroke in humans, which occurs when a clot blocks blood flow and neurons die in the affected brain region. Results showed that daily gabapentin treatment for six weeks after a stroke restored fine motor functions in the animals’ upper extremities. Functional recovery also continued after treatment was stopped, the researchers found.</p>
<p>“Stroke causes devastating sensory-motor deficits and long-term disability due to disruption of descending motor pathways. Restoration of these functions enables independent living and therefore represents a high priority for those afflicted by stroke. Here, we report that daily administration of gabapentin, a clinically approved drug already used to treat various neurological disorders, promotes structural and functional plasticity of the corticospinal pathway after photothrombotic cortical stroke in adult mice,” the investigators wrote.</p>
<p>“We found that gabapentin administration had no effects on vascular occlusion, hemodynamic changes, nor survival of corticospinal neurons within the ipsilateral sensory-motor cortex in the acute stages of stroke. Instead, using a combination of tract tracing, electrical stimulation, and functional connectivity mapping, we demonstrated that corticospinal axons originating from the contralateral side of the brain in mice administered gabapentin extend numerous collaterals, form new synaptic contacts and better integrate within spinal circuits that control forelimb muscles.</p>
<p>“Not only does gabapentin daily administration promote neuroplasticity, but it also dampens maladaptive plasticity by reducing the excitability of spinal motor circuitry. “In turn, mice administered gabapentin starting one hour or one day after stroke recovered skilled upper extremity function. Functional recovery persists even after stopping the treatment at six weeks following a stroke.</p>
<p>“Finally, chemogenetic silencing of cortical projections originating from the contralateral side of the brain transiently abrogated recovery in mice administered gabapentin, further supporting the conclusion that gabapentin-dependent reorganization of spared cortical pathways drives functional recovery after stroke. These observations highlight the strong potential for repurposing gabapentinoids as a promising treatment strategy for stroke repair.”</p>
<h4><strong>Gabapentin found to block protein activity</strong></h4>
<p>The Ohio State University team previously found that gabapentin blocks the activity of a protein that, when expressed at elevated levels after an injury to the brain or spinal cord, hinders re-growth of axons, the long, slender extensions of nerve cell bodies that transmit messages.</p>
<p>“When this protein is high, it interferes with neurological recovery,” said lead author Andrea Tedeschi, PhD, assistant professor of neuroscience, in the Ohio State’s College of Medicine.</p>
<p>“Imagine this protein is the brake pedal, and recovery is the gas pedal. You can push on the gas pedal but can’t accelerate as long as you’re also pushing on the brake pedal,” Tedeschi said. “If you start lifting the brake pedal and continuously press on the gas, you can really speed up recovery. We think that is gabapentin’s effect on neurons, and there is a contribution of non-neuronal cells that tap into this process and make it even more effective.”</p>
<p>This work builds upon a 2019 study in which Tedeschi’s lab found in mice that gabapentin helped restore upper limb function after a spinal cord injury.</p>
<p>The primary treatment focus after an ischemic stroke is re-establishing blood flow in the brain as quickly as possible, but this research suggests that gabapentin has no role at that acute stage: The recovery results were similar whether the treatment started one hour or one day after the stroke.</p>
<p>Instead, the drug’s effects are evident in specific motor neurons whose axons carry signals from the central nervous system to the body that tell muscles to move.</p>
<p>After the stroke in study mice, the researchers observed, that neurons on the undamaged, or contralateral, side of the brain began sprouting axons that restored signals for upper extremity voluntary movement that had been silenced by neuron death after the stroke. This is an example of plasticity, the central nervous system’s ability to fix damaged structures, connections, and signals.</p>
<p>“The mammalian nervous system has some intrinsic ability to self-repair,” said Tedeschi, also a member of the Ohio State’s Chronic Brain Injury Program. “But we found this increase in spontaneous plasticity was not sufficient to drive recovery. The functional deficits are not so severe in this experimental model of ischemic stroke, but they are persistent.”</p>
<p>Because a technique that temporarily silenced the new circuitry reversed behavioral signs of recovery, Tedeschi said the findings suggested the drug normalizes conditions in the damaged nervous system to promote cortical reorganization in a functionally meaningful way.</p>
<p>Compared to control mice that did not receive the drug, mice that received six weeks of daily gabapentin treatment regained fine motor function in their forelimbs. Two weeks after treatment was stopped, researchers observed, functional improvements persisted.</p>
<p>“This confirmed that functional changes are solidified in the nervous system,” Tedeschi said.</p>
<p>Gabapentin also appeared to have an effect in the stroke-affected brain on non-neuron cells that influence the timing of message transmission. An examination of their activity after the drug treatment suggested these cells can dynamically change their behavior in response to variations in synaptic communication, further enabling smooth sprouting of axons that were compensating for the lost neurons.</p>
<p>The team is continuing to study the mechanisms behind stroke recovery, but Tedeschi said the findings suggest gabapentin holds promise as a treatment strategy for stroke repair. <a href="https://www.genengnews.com/topics/translational-medicine/anticonvulsant-drug-may-boost-functional-recovery-after-a-stroke/" target="_blank" rel="noopener">source</a></p>
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<h1 class="mb-4 h1 sm:pr-8 md:pr-12 xl:pr-16">This already-approved drug could help repair the brain after stroke</h1>
<div class="mb-9 h5 sm:pr-8 md:pr-12 xl:pr-16 xl:mb-0">The common drug gabapentin helped restore motor function in animals after a stroke.</div>
<div>
<p>hio State scientists have discovered that an already approved and widely prescribed drug, called gabapentin, may help the brain repair itself after a stroke.</p>
<p>Gabapentin is currently used to control seizures and help manage nerve pain, but in mice with blood clot-induced strokes, the drug helped the animals  regain fine motor control in their upper limbs, with lasting improvement even after the treatment ended.</p>
<p>The discovery builds off of previous research, where the investigators learned that gabapentin blocks a protein in the brain that can hinder healing.</p>
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<blockquote><p>Over 600,000 people suffer a first stroke per year.</p></blockquote>
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<p>“When this protein is high, it interferes with neurological recovery,” Andrea Tedeschi, assistant professor of neuroscience at Ohio State, said in a statement.</p>
<p>He compared the protein to a brake pedal in a car. If you’re jamming down on the brake, you won’t go too far, no matter how hard you push on the gas pedal.</p>
<p>“If you start lifting the brake pedal and continuously press on the gas, you can really speed up recovery,” Tedeschi said. “We think that is gabapentin’s effect on neurons, and there is a contribution of non-neuronal cells that tap into this process and make it even more effective.”</p>
<p><strong>Stroke recovery: </strong>An ischemic stroke is caused by a clot choking off blood supply to part of the brain, leading to the death of brain cells in the impacted region.</p>
<p>This can lead to long term complications, including loss of muscle use, difficulty talking and swallowing, and emotional and memory issues.</p>
<div>
<div id="ft_content2" class="advertising advertising--inline" data-google-query-id="CMS25_DegP0CFSe2AAAdiwEJJw">
<div id="google_ads_iframe_/1037571/ft_content2_0__container__">“Restoration of these functions enables independent living and therefore represents a high priority for those afflicted by stroke,” the researchers wrote in their study, published in Brain.</div>
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<p>According to the CDC, over 600,000 people suffer a first stroke each year, which means millions of people will need help recovering in the next few years alone.</p>
<blockquote class="wp-block-quote"><p>Scientists have discovered that an already approved and widely prescribed drug, called gabapentin, may help the brain repair itself after a stroke.</p></blockquote>
<p><strong>The natural repair system: </strong>The first level treatment for ischemic stroke is to re-establish blood flow as quickly as possible, but the researchers found that this crucial step had no impact on gabapentin’s effectiveness, with motor function improvement happening whether the mice received the drug an hour or a day after stroke onset.</p>
<p>After the mice suffered a stroke, the neurons responsible for sending signals to the muscles from the undamaged sides of their brains began sprouting axons to form new connections, something popularly referred to as “plasticity” — the ability of different parts of the brain to adapt and repair damaged circuits and structures.</p>
<p>“The mammalian nervous system has some intrinsic ability to self-repair,” Tedeschi said, but not enough.</p>
<p>Injured neurons may become “hyperexcited,” firing signals that can cause muscle contractions and pain. If a brain protein called alpha2delta2 is expressed too much after a damaging incident like a stroke, it can contribute to this condition, while also slowing down axon growth.</p>
<p><strong>A better fix:</strong> Gabapentin inhibits this protein, allowing the nerve cells to regrow and reorganize more efficiently and effectively.</p>
<p>“We blocked the receptor with the drug and asked, will even more plasticity occur? The answer is yes,” Tedeschi said.</p>
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<blockquote><p>Gabapentin restored forelimb motor control in mice.</p></blockquote>
</figure>
<p>Mice that received gabapentin daily for six weeks regained fine motor control in their forelimbs, which lasted for up to two weeks after dosing stopped; control mice who did not receive gabapentin did not regain motor control.</p>
<p>While a far cry from a sure thing in humans, the researchers believe that their study could be a first step towards finding a new use for an already-approved drug. Because the drug is already so widely used and understood, trials in humans may be faster and easier than for new drugs.</p>
<p>“These observations highlight the strong potential for repurposing gabapentinoids as a promising treatment strategy for stroke repair,” they wrote. <a href="https://www.freethink.com/health/gabapentin-stroke-recovery" target="_blank" rel="noopener">source</a></p>
<p><em>We’d love to hear from you! If you have a comment about this article or if you have a tip for a future Freethink story, please email us at tips@freethink.com.</em></p>
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		<title>Top 7 Vitamins for Stroke Recovery Based on the Latest Clinical Evidence</title>
		<link>https://goodshepherdmedia.net/top-7-vitamins-for-stroke-recovery-based-on-the-latest-clinical-evidence/</link>
		
		<dc:creator><![CDATA[The Truth News]]></dc:creator>
		<pubDate>Thu, 06 Jan 2022 11:05:27 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Healthy Living]]></category>
		<category><![CDATA[Herbs & Supplements]]></category>
		<category><![CDATA[Physical Health]]></category>
		<category><![CDATA[Top Stories]]></category>
		<category><![CDATA[Zee Truthful News]]></category>
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		<category><![CDATA[🧠Stroke⚕️🏥]]></category>
		<category><![CDATA[Clinical Evidence]]></category>
		<category><![CDATA[Latest]]></category>
		<category><![CDATA[Latest Clinical Evidence]]></category>
		<category><![CDATA[Supplements]]></category>
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		<category><![CDATA[Vitamins for Stroke Recovery]]></category>
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					<description><![CDATA[Top 7 Vitamins for Stroke Recovery Based on the Latest Clinical Evidence Vitamins for stroke recovery can help boost brain health, but beware that no single pill fits all. Supplements that enhance one person’s recovery from stroke may worsen recovery in someone else. To avoid this mistake, learn why some stroke supplements can be dangerous [&#8230;]]]></description>
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<h1 class="elementor-heading-title elementor-size-default" style="text-align: center;">Top 7 Vitamins for Stroke Recovery Based on the Latest Clinical Evidence</h1>
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<p>Vitamins for stroke recovery can help boost brain health, but beware that no single pill fits all.</p>
<p>Supplements that enhance one person’s recovery from stroke may worsen recovery in someone else. To avoid this mistake, learn why some stroke supplements can be dangerous for you.</p>
<p>Then, we’ll share an updated list of the best vitamins to enhance stroke recovery.</p>
<h2>Take Supplements for Stroke Recovery with Extreme Caution</h2>
<p>Before we dig into the list of science-backed vitamins and supplements for stroke recovery, you need to proceed with caution.</p>
<p>It is imperative that you consult with your physician before adding supplements to your regimen. Some supplements can interfere with certain medications to worsen your health status and cause complications.</p>
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<p>For example, <strong>ginko biloba</strong> is an herb that is used to help prevent ischemic stroke (the type of stroke caused by a clot) because it’s a natural blood thinner…</p>
<p>However, it can also put people with a history of hemorrhagic stroke (the type of stroke caused by a bleed) at an increased risk of suffering a second stroke. Additionally, complications can arise if you’re already taking blood thinning medication.</p>
<p>Other supplements that contain natural blood thinning properties include: turmeric, ginger, cayenne pepper, vitamin E, garlic, cassia cinnamon, grape seed extract, omega 3s, and bromelain.</p>
<p>Now, let’s dig into the list of the top supplements and vitamins for stroke recovery.</p>
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<p><strong>Want 20 pages of stroke recovery tips in an illustrated PDF? </strong>Download our free ebook by clicking here (link opens a pop up for uninterrupted reading)</p>
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<h2>The Best Science-Backed Vitamins for Stroke Recovery</h2>
<p>Based upon relevant clinical research, here are the best supplements and vitamins for stroke recovery:</p>
<h3>1. Vitamin D</h3>
<p>Research studies show that vitamin D is one of the best vitamins for stroke recovery.</p>
<p>Low levels of vitamin D are associated with worse outcomes after ischemic stroke, which account for 87% of all strokes in America. Furthermore, vitamin D deficiency is associated with the stroke risk factors like hypertension, obesity, and diabetes. (Source: Current Opinion in Clinical Nutrition and Metabolic Care)</p>
<p>Fortunately, after supplementing with vitamin D, “there is a significant improvement in stroke outcomes after 3 months.” (Source: Journal of Clinical and Diagnostic Research)</p>
<p>Getting enough vitamin D can also provide neuroprotective, neuromuscular, and osteoprotective benefits which can reduce cognitive and functional impairments in individuals after a stroke. (Source: Current Drug Targets)</p>
<p>By getting your daily dose of vitamin D, you can reduce your risk of another stroke while aiding your brain’s recovery.</p>
<p><strong>How to get vitamin D naturally:</strong></p>
<p>Your body can produce Vitamin D, known as the sunshine vitamin, from daily amounts of sun exposure. As always, be cautious about your exposure during peak hours (generally 10am-4pm) when the sun’s rays are the strongest.</p>
<p>If you can’t get sun exposure due to medical restrictions (like heightened risk of skin cancer), then consume it through foods that are high in Vitamin D, like fatty fish, cheese, and egg yolks.</p>
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<p>Vitamin D deficiency is associated with poor outcomes after stroke, whereas daily supplementation is associated with better outcomes.</p>
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<h3>2. Probiotics</h3>
<p>Probiotics aren’t a vitamin or mineral. Rather, probiotics are the “good” bacteria that comprise your microbiome, the 100 trillion microbes that live inside your gut.</p>
<p>The bacteria living inside your body serve an important role – they even have a nervous system of their own called the <em>enteric nervous system</em>.</p>
<p>Through this internal ecosystem, the bacteria in your gut communicate with your brain through the <em>gut-brain axis</em>. This connection is <strong>bidirectional</strong>, which means that it goes both ways. (Source: Annals of Gastroenerology)</p>
<p>Since gut health plays a key role in brain health, probiotics make the list of top supplements for stroke recovery.</p>
<p><strong>How to get probiotics naturally:</strong></p>
<p>Great dietary sources of probiotics include fermented foods like yogurt, kefir, tempeh, kimchi, and miso.</p>
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<p>You need “good” bacteria to support your microbiome, which influences brain health and function via the gut-brain axis.</p>
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<h3>3. Vitamin B12</h3>
<p>Vitamin B12 deficiency is associated with a type of inflammation that damages the blood vessels. When blood vessels become damaged, excess deposits can develop and interrupt blood flow. If this happens to an artery in the brain, it can lead to a stroke. (Source: VeryWell Health)</p>
<p>Supplementing with vitamin B12 can enhance stroke recovery by boosting the function and development of the brain and nerve cells. (Source: Viatcheslav Wlassoff, PhD)</p>
<p>This encourages neuroplasticity, which is the brain’s ability to reorganize itself, create new neural pathways, and rearrange existing ones.</p>
<p><strong>How to get vitamin B12 naturally:</strong></p>
<p>Vitamin B12 can be found in animal products like fish, meat, poultry, eggs, and milk. If you have a history of stroke risk factors like high cholesterol or atherosclerosis, consume lean sources of protein such as fish or poultry.</p>
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<p>Vitamin B12 provides essential support for both brain and blood vessel health.</p>
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<h3>4. Vitamin B3 (Niacin)</h3>
<p>Vitamin B3, also known as niacin, can encourage recovery of brain function after stroke for two main reasons:</p>
<p>First, niacin directly affects neuroplasticity, which is the primary driver of recovery from stroke. Secondly, niacin has been proven to improve “good” cholesterol levels, which are statistically low in stroke survivors. (Source: MedicineNet)</p>
<p>Although experts have yet to link “good” cholesterol levels with stroke recovery, reducing one’s risk of a second stroke is a significant accomplishment.</p>
<p><strong>How to get niacin naturally:</strong></p>
<p>You can find vitamin B3 in tuna, chicken, turkey, and salmon. For meatless options, you can find lesser quantities of niacin in peanuts and brown rice.</p>
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<p>Vitamin B3 positively affects neuroplasticity, which is driving mechanism of stroke recovery.</p>
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<h3>5. DHA (Docosahexaenoic acid)</h3>
<p>DHA is an omega-3 fatty acid that is critical for healthy brains. While omega-3s are not vitamins, they still made the list for their positive effects on stroke recovery.</p>
<p>DHA is essential for brain growth in infants and maintenance of normal brain function in adults. Some studies suggest that DHA can reduce stroke risk factors like hypertension and atherosclerosis. (Source: Pharmacological Research)</p>
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<p>Be aware that fish oil is contraindicated for some blood thinners, such as Warfarin. Check with your physician to see if this supplement is safe for you. (Source: Annals of Pharmacotherapy)</p>
<p><strong>How to get DHA:</strong></p>
<p>DHA is an essential fatty acid, meaning your body cannot produce it on its own – you must get it from your diet (or supplements).</p>
<p>Fatty fish, like salmon, contain healthy amounts of DHA. If you are on a strict heart healthy diet, then consider taking fish oil supplements to obtain your daily amount of DHA.</p>
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<p>DHA can improve healthy brain function and must be consumed through diet or supplements.</p>
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<h3>6. Coenzyme Q10 (CoQ10)</h3>
<p>CoQ10 is most famous for improving heart health – but it holds incredible benefits for your brain, too. This is why CoQ10 made the list of top vitamins for stroke recovery, even though it’s a nutrient and not a vitamin.</p>
<p>CoQ10 is a powerful antioxidant that provides protection from free radicals, which are toxic molecules associated with disease. Free radicals are believed to play a role in cardiovascular disease, which is a precursor to stroke.</p>
<p>By supplementing with CoQ10, you can improve your heart health and, therefore, reduce your risk of a second stroke.</p>
<p>Also, low CoQ10 levels have been associated with greater tissue damage to the brain during stroke.</p>
<p><strong>How to get CoQ10 naturally:</strong></p>
<p>CoQ10 can be found in most liver organ meats like heart, liver, and kidney. However, these meats also contain high amounts of cholesterol and saturated fats that exacerbate cardiovascular disease.</p>
<p>Small amounts of CoQ10 can be found in spinach, broccoli, and cauliflower. Due to this, supplementation may be more suitable for individuals recovering from a stroke.</p>
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<p>CoQ10 can boost recovery from stroke by protecting you from damaging free radicals associated with cardiovascular disease.</p>
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<h3>7. Vitamin C</h3>
<p>Vitamin C deficiency may be a stroke risk factor, especially in individuals with a history of hemorrhagic strokes (the type of stroke caused by a burst artery in the brain).</p>
<p>In a study from the American Academy of Neurology, 65 survivors of hemorrhagic stroke were compared to 65 healthy people. On average, those who suffered a stroke had depleted levels of vitamin C while healthy people did not.</p>
<p>Study author Stephane Vannier, MD, concluded that “vitamin C deficiency should be considered a risk factor for this severe type of stroke.”</p>
<p><strong>How to get vitamin C naturally:</strong></p>
<p>Although oranges are well-known for their nutritional benefits, other fruits and vegetables, like papaya, bell peppers, broccoli, and strawberries, contain higher amounts of vitamin C.</p>
<p>Dr. Stephane Vannier, from Pontchaillou University Hospital in Rennes, does not recommend supplementing vitamin C if you are not deficient.</p>
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<p>People with a history of hemorrhagic stroke should pay attention to their vitamin C levels to promote overall health and wellness.</p>
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<h2>How to Get These Stroke Supplements without Breaking Your Budget</h2>
<p>Consider obtaining these supplements through your diet as opposed to costly pills and herbal remedies.</p>
<p>Eat a variety of whole foods every day, especially foods that help stroke recovery, in order to avoid developing a nutritional deficiency. Prioritize meals with minimal processing, which can strip foods of essential vitamins and minerals.</p>
<p>If you are unable to consume these vitamins and minerals through your diet, then consult with your physician prior to adding supplement to your medication regimen.</p>
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<p>Medically reviewed by Andrew Tran PT, DPT, NCS, CSCS <a href="https://www.flintrehab.com/vitamins-for-stroke-recovery/" target="_blank" rel="noopener">source</a></p>
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<h3><strong>always consult with your physician!</strong> <img loading="lazy" decoding="async" class="size-full wp-image-11261 alignleft" src="https://goodshepherdmedia.net/wp-content/uploads/2023/02/warning.jpg" alt="" width="150" height="150" /></h3>
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		<title> tPA a plasminogen activator used in HIV Treatment could improve recovery after stroke</title>
		<link>https://goodshepherdmedia.net/tpa-a-plasminogen-activator-used-in-hiv-treatment-could-improve-recovery-after-stroke/</link>
		
		<dc:creator><![CDATA[The Truth News]]></dc:creator>
		<pubDate>Fri, 31 Dec 2021 11:10:53 +0000</pubDate>
				<category><![CDATA[Health]]></category>
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		<category><![CDATA[🧠Brain Health🧠]]></category>
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		<category><![CDATA[after stroke]]></category>
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					<description><![CDATA[ tPA a plasminogen activator used in HIV Drug Treatment could improve recovery after stroke A protein that may hinder the brain’s regrowth after damage points researchers to an unexpected treatment Stroke treatment has been a race against time. In the hours after a stroke, the clot-busting treatment tissue plasminogen activator (tPA) can limit damage to the [&#8230;]]]></description>
										<content:encoded><![CDATA[<h1 class="news-article__hero__title" style="text-align: center;"> tPA a plasminogen activator used in HIV Drug Treatment could improve recovery after stroke</h1>
<h2 class="news-article__hero__subtitle h5 font-weight-normal serif mt-1" style="text-align: center;">A protein that may hinder the brain’s regrowth after damage points researchers to an unexpected treatment</h2>
<p>Stroke treatment has been a race against time. In the hours after a stroke, the clot-busting treatment tissue plasminogen activator (tPA) can limit damage to the brain. But once that damage is done, no drugs are known to promote recovery. New research suggests such a therapy could come from an unlikely target: <a href="https://www.cell.com/cell/fulltext/S0092-8674(19)30107-2">a cellular protein called CCR5 that allows HIV to infect cells</a>. Scientists found that in mice, disabling CCR5 helps surviving neurons make new connections, and that people who carry a CCR5 mutation may recover better from a stroke.</p>
<p>&#8220;This is the first real molecular target to improve recovery after stroke,&#8221; says Argye Hillis, a stroke neurologist at Johns Hopkins University School of Medicine in Baltimore, Maryland, who was not involved in the work. A clinical trial will soon test its promise by giving stroke patients an HIV drug that blocks CCR5.</p>
<p>White blood cells display CCR5 on their surface to intercept signals from molecules called chemokines and coordinate an immune response. But HIV exploits CCR5, grabbing onto it to invade host cells. People with a mutation that cripples the <em>CCR5</em> gene are protected from infection, which is why Chinese scientist He Jiankui recently aimed to mutate <em>CCR5</em> in <a href="http://science.sciencemag.org/content/362/6418/978?adobe_mc=MCMID%3D13053749737729956373080267700945088432%7CMCORGID%3D242B6472541199F70A4C98A6%2540AdobeOrg%7CTS%3D1675660381">controversial human experiments</a>.</p>
<p>The new discoveries about CCR5 began with a hunt for &#8220;smart mice&#8221;—animals bearing genetic mutations that apparently boost their ability to learn and remember. Neuroscientist Alcino Silva and his team at the University of California, Los Angeles (UCLA), wanted to figure out which of 148 mouse strains had such enhancements. In 2016, they reported that reducing levels of CCR5 in a healthy mouse brain enhanced memory formation and learning.</p>
<p>UCLA stroke neurologist Thomas Carmichael was intrigued. &#8220;When you watch patients recover in stroke, it looks like they&#8217;re relearning to walk or relearning language,&#8221; he says. Indeed, surviving neurons near the injury sprout tendrils to make new contacts across the brain. A drug that targets CCR5 seemed promising for stroke recovery, and that drug was already on hand. Maraviroc, which blocks CCR5, was approved by U.S. regulators in 2007 for use with other antiretroviral drugs to treat HIV infections.</p>
<p>In <em>Cell</em> this week, Silva, Carmichael, and their collaborators showed that CCR5 levels in mouse neurons skyrocket after stroke and can remain elevated for weeks—and that the protein appears to hamper recovery. The team blocked CCR5 with maraviroc or a gene that interferes with its production, and then ran the mice through tests of motor ability—for example, counting how many times their feet slipped as they walked across a metal grid. Treated mice showed greater motor improvements than controls at the end of the 9-week testing period.</p>
<p>Even if the researchers waited until 3 weeks after a stroke to give the animals maraviroc, it improved their performance. In previous studies, nothing has seemed to help at that point, says Dale Corbett, a neuroscientist specializing in stroke recovery at the University of Ottawa. The new results, he says, suggest &#8220;it may be feasible to reopen this recovery window in people.&#8221;</p>
<p>Blocking CCR5 seemed to help maintain connections between neurons adjacent to the injured site. And it caused neurons in motor regions to sprout more projections to the opposite side of the brain, a process that might help a mouse relearn lost movements.</p>
<p>What CCR5 does in the poststroke brain is hazy. Surging CCR5 is part of the inflammatory response to stroke, says Robyn Klein, a neuroimmunologist at Washington University School of Medicine in St. Louis, Missouri. In flammatory molecules may prompt neurons to express more of this chemokine receptor. In the developing brain, chemokines are known to influence how neurons migrate and connect. After stroke, they seem to decrease the number of connection sites on neurons near the damage. (How that process hinders regrowth and recovery isn&#8217;t clear.)</p>
<p>Carmichael notes that blocking CCR5 also caused neurons to express genes that increase their excitability, making them fire more readily. He suspects that neurons boost CCR5 after a stroke to dampen their activity and lie low to avoid a deadly cellular frenzy known as excitotoxicity. But because the protein then sticks around, that protective mechanism gets in the way of recovery.</p>
<p>Mouse results often prove meaningless in people, but when Carmichael&#8217;s group teamed up with researchers behind the Tel Aviv Brain Acute Stroke Cohort (TABASCO) in Israel, they found encouraging clues. Roughly 10% of Europeans have a genetic deletion that cripples CCR5, and the number is higher in Jewish people of Eastern European origin. The TABASCO team identified 68 people in its cohort of stroke survivors who had at least one copy of the CCR5 mutation. Compared with people without the mutation, they performed slightly better on tests of motor and sensory skills and cognitive abilities both 6 months and 1 year after a stroke, the new study found.</p>
<p>&#8220;It wasn&#8217;t gangbusters better, but … the fact that they found anything is impressive,&#8221; says Steven Cramer, a stroke neurologist at UC Irvine, who has studied genes linked to stroke recovery.</p>
<p>Carmichael and his collaborators are now designing a clinical trial that will give 30 people maraviroc starting when they leave an inpatient rehabilitation facility—typically about 4 weeks after a stroke. The team hopes to launch the trial this year.</p>
<p>Meanwhile, some researchers expect the CCR5 story to inspire a broader search for brain repair strategies based on learning and memory genes. &#8220;We&#8217;ve always been talking about having a tPA-like moment for stroke recovery,&#8221; Corbett says. &#8220;Whether this is it or not, I don&#8217;t know, but at least it gives us hope.&#8221;</p>
<p><a href="https://www.science.org/content/article/hiv-drug-could-improve-recovery-after-stroke" target="_blank" rel="noopener">source</a></p>
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